Comparative Evaluation of Serum Ceruloplasmin in Chronic and Aggressive Periodontitis Patients: A Cross-Sectional Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Background: Pro-inflammatory markers have come a long way as indicators of periodontal disease. One such marker which can be detected in the serum is the ceruloplasmin. The aim of this study was to evaluate the serum levels of cerruloplasmin in both aggressive and chronic periodontitis patients. Materials and Methods: Blood samples were collected from aggressive periodontitis patients(n = 20), chronic periodontitis patients(n = 20) and periodontally healthy patients (n = 20). The serum was extracted from all the blood samples and ceruloplasmin levels were spectroscopically evaluated. Results: Periodontally healthy patients did not show increase in the levels of serum ceruloplasmin. Serum ceruloplasmin levels were found to be significantly higher in aggressive periodontitis patients (P > 0.05) than in chronic periodontitis patients (P > 0.05) even though increase in the level of ceruloplasmin was found in chronic periodontitis. The levels of serum ceruloplasmin also increased with the disease severity. Conclusion: Serum ceruloplasmin levels increased in both aggressive and chronic periodontitis patients, but more in aggressive periodontitis patients. Thus it can be used as a potential marker for the diagnosis of periodontitis.
Authors and Affiliations
Dr. Prabhati Gupta, Dr. Abhima Kumar
Keywords
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- EP ID EP467560
- DOI 10.9790/0853-1802086972.
- Views 52
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