Comparative Evaluation of Serum Ceruloplasmin in Chronic and Aggressive Periodontitis Patients: A Cross-Sectional Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Background: Pro-inflammatory markers have come a long way as indicators of periodontal disease. One such marker which can be detected in the serum is the ceruloplasmin. The aim of this study was to evaluate the serum levels of cerruloplasmin in both aggressive and chronic periodontitis patients. Materials and Methods: Blood samples were collected from aggressive periodontitis patients(n = 20), chronic periodontitis patients(n = 20) and periodontally healthy patients (n = 20). The serum was extracted from all the blood samples and ceruloplasmin levels were spectroscopically evaluated. Results: Periodontally healthy patients did not show increase in the levels of serum ceruloplasmin. Serum ceruloplasmin levels were found to be significantly higher in aggressive periodontitis patients (P > 0.05) than in chronic periodontitis patients (P > 0.05) even though increase in the level of ceruloplasmin was found in chronic periodontitis. The levels of serum ceruloplasmin also increased with the disease severity. Conclusion: Serum ceruloplasmin levels increased in both aggressive and chronic periodontitis patients, but more in aggressive periodontitis patients. Thus it can be used as a potential marker for the diagnosis of periodontitis.
Authors and Affiliations
Dr. Prabhati Gupta, Dr. Abhima Kumar
Keywords
Related Articles
- EP ID EP467560
- DOI 10.9790/0853-1802086972.
- Views 68
- Downloads 0
Acute Transfusion Reactions in Intensive Care Unit: A Retrospective Study
Blood transfusion is a frequent and integral part of critical care. Although life saving it can occasionally be unsafe and results in spectrum of adverse events. Acute transfusion reactions (ATRs) are probably under diag...
A Three Year Old Girl with WaldenstromMacroglobulinemiaA Rare Case Study
Waldenstrommacroglobulinemia a chronic beta cell lymphoproliferative disorder characterised by IgM monoclonal gammopathy, bone marrow infiltration by lymphocyte, lymphocytoid cells & plasma cells.It accounts for approx....
Pattern of Annual Distribution and Prevalence of Type 2 Diabetes Mellitus amongst Adult Patients at Government House Clinic, Umuahia, Abia State, Nigeria: Ten Years in Retrospect
This study investigated the pattern of yearly frequency distribution, as well as annual prevalence rate of type 2 diabetes mellitus (T2DM) amongst adult patients attending diabetes clinics at Government house clinic, Umu...
Application of Intracanal Medicaments: A Review
Elimination of microorganisms from the root canal is the main procedure for endodontic treatment. Cleaning and shaping is not so much effective for reducing bacterial count in root canals. This procedure may fail due to...
Efficacy of Epidural Steroid as a Pain Management Modality In Scoliotic Patient
.