Comparative Evaluation of Three Cytological Grading Systems for Carcinoma Breast
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 2
Abstract
Background: Fine needle aspiration cytology is an important tool in the diagnosis, prognosis and management of breast carcinoma. It has been recommended that cytological grading should be included in the FNA reports to know the tumor aggressiveness and prognostication. Among the many cytological grading systems existing, there is still no agreement on the most reliable system. Aim: The study was undertaken to evaluate three cytological grading systems and correlate with histological grading by Nottingham modification of Scarff Bloom Richardson (SBR) method. Materials and Methods: Cytological grading by Robinson’s grading, Fisher’s modification of Black nuclear grading and Howell grading systems was done on 50 carcinoma breast cases. Histological grading by Nottingham modification of SBR grading was done. Cytohistologic grading correlation was done by testing concordance, association and correlation. Results: The three cytological grading systems correlated well with histological grading. Fisher’s modification of Black nuclear grading system demonstrated the best correlation ( = 0.61; P < 0.001) and concordance (Percent of agreement=70%) with the SBR’s grading system.Conclusions: Fisher’s modification of Black nuclear grading system is simple, reproducible and showed the best concordance with histological grading
Authors and Affiliations
Susmitha M. S.
Keywords
Related Articles
- EP ID EP464288
- DOI 10.21088/ijprp.2278.148X.62(pt-II)17.20
- Views 96
- Downloads 0
Histopathological Spectrum of Laparoscopic Sleeve Gastrectomies: A Retrospective Study
Objective: This study was carried out to evaluate the spectrum of histopathological lesions in laparoscopic sleeve gastrectomies in morbidly obese patients at a tertiary care hospital in rural Haryana. Methodology: It wa...
Significance of Masood’s Scoring Index in Cytological Diagnosis of Palpable Breast Lumps: A 3 Years Restrospective Studies
Introduction: Breast lump is the commonest presentation of breast diseases. Diagnosis of breast diseases can be made out based on history, physical examination and investigations, like cytology, histology and radiology....
A Study on Histopathological Patterns of Thyroid Lesions and its Cytological Correlation: An Experience of A Rural Tertiary Care Center
Objective: Thyroid lesions are the most common endocrine problem encountered in routine clinical practice. This study describes the various spectrums of thyroid lesions in surgically resected specimen and its correlation...
Morphological Characterisation of Capillary Hemangioma Pattern: An Indian Study
Context: Capillary hemangiomas are fairly common benign tumors encountered across all age groups.Even though they consist of number of clinicopathologically distinct entities, clinicians and pathologists alike have tradi...
Coexistent Erythema Nodosum Leprosum with Tubercular lymphadenitis in an Immunocompetent Individual: An Unusual Association
Leprosy and tuberculosis are chronic granulomatous diseases known to be endemic in our country. Simultaneous occurrence of both infections in a single individual is not an uncommon clinical condition but has been reporte...