Comparative Evaluation of two Different Intravenous Doses of Midazolam to Aid the Insertion of LMA Classic as Adjuvants to Propofol Anaesthesia
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 3
Abstract
Background: Propofol is a widely accepted medication for the uccessful insertion of laryngeal mask airway, but as a sole induction agent, it has a very low success rate. A number of co-induction agents have been used with propofol to increase the success rate of LMA insertion. Aim and Objectives: To evaluate the efficacy of two different doses of midazolam i.e. 0.05 mg/kg and 0.08 mg/kg intravenously when used with propofol versus propofol alone for LMA insertion. To find the appropriate dose of midazolam that provides ideal condition and maximum haemodynamic stability. Material & Methods: 75 adult patients of ASA I & II grade randomly divided into 3 groups. Group P: Propofol + Saline Group PM1: Midazolam 0.05 mg/kg 3 minutes before propofol + Propofol Group PM2: Midazolam 0.08 mg/kg 3 minutes before propofol + Propofol. LMA insertion attempted 1 minute after the administration of Propofol. Total dose of propofol used, the insertion conditions and haemodynamic changes were noted. Results: There was no statistical difference in demographic profile. Haemodynamically patients were more stable in group PM1 & PM2 than in group P. Dose of propofol used in PM2 (2.05+0.21 in mg/kg) & PM1 (2.38+0.21) was less than in Group P (2.84 mg/kg). 100% success rate in LMA insertion was observed in group PM1 & PM2 in first attempt whereas it was 80% in group P. 88% in group PM2, 60% in group PM1 & only 32% patients in group P had excellent insertion conditions. Conclusion: Propofol as a sole agent does not provide LMA insertion conditions. Midazolam when used with propofol provides adequate conditions for LMA insertion in a dose dependent manner.
Authors and Affiliations
Geetanjali Pushkarna
Keywords
Related Articles
- EP ID EP619605
- DOI 10.21088/ijaa.2349.8471.6319.1
- Views 88
- Downloads 0
Evaluation of Propofol with Propofol -Midazolam for I-gel Insertion in Impulsively Breathing Patients for Elective Day Care Procedures
Background and Aim: The I-gel is the innovative second generation supraglottic airway device from Intersurgical. I-gel offers unique advantages of easy insertion, reduced trauma, superior sealing pressure, and gastric ac...
Comparison of Two doses of Melatonin for Pre-Operative Anxiolysis in Adult Patients
This study was done to determine the efficacy of melatonin as a pre-operative anxiolytic and to compare the effect of two different doses of melatonin for the same. Settings and Design: This is a randomised double blinde...
A Comparative Study of Low Doses of Intrathecal Ketamine and Midazolam with Bupivacaine for Infraumbilical Surgeries
Aim: The aim of this study is to evaluate the effect of the low doses of ketamine and midazolam with bupivacaine intrathecally in terms of duration of analgesia and haemodynamic parameters. Materials and Methods: This...
A Prospective Comparative Study of Efficacy and Safety of Dexmedetomidine as an Adjuvant to Caudal Levobupivacaine Versus Levobupivacaine Alone in Paediatric Patient
Background: As the day care surgery becomes popular, caudal epidural block has become routine intervention in children and infants. But the major limitation with this technique is duration of analgesia after single injec...
Hyomental Distance in Neutral and Extension as a Clinically Reliable Predictor of Difficult Airway
Aims: This study was been done with a purpose to evaluating the benifit of the Hyomental Distance [Hmd] neutral and extended position for predicting accurately difficult visualization of the larynx (DVL) in normal lookin...