COMPARATIVE INVESTIGATION OF ANTIDIABETIC ACTIVITY OF ACARBOSE, MIGLITOL AND SALACIA OBOLNGA IN PATIENTS OF TYPE 2 DIABETES MELLITUS
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Acarbose, Miglitol and Voglibose are the marketed ?-glucosidase inhibitor used to reduce post prandial glucose level in the patients of type 2 diabetes mellitus. Increased post prandial blood is cause of number of disease in such patients. Salacia Oblonga and Salacia Reticulata are plants native to India and Sri Lanka these are widely used for thousands of years in Ayurvedic medicine for the oral treatment of diabetes, Attenuation of postprandial glycemia is hypothesized to reduce the risk of progression from impaired glucose tolerance to diabetes. It is also thought to reduce the number of complications associated with diabetes. A clinical trial conducted to assess the comparison of outcome of marketed drugs and with salacia oblonga, found significant effect on weight and HbA1C value of patients of Type II DM.
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