COMPARATIVE INVESTIGATION OF ANTIDIABETIC ACTIVITY OF ACARBOSE, MIGLITOL AND SALACIA OBOLNGA IN PATIENTS OF TYPE 2 DIABETES MELLITUS
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Acarbose, Miglitol and Voglibose are the marketed ?-glucosidase inhibitor used to reduce post prandial glucose level in the patients of type 2 diabetes mellitus. Increased post prandial blood is cause of number of disease in such patients. Salacia Oblonga and Salacia Reticulata are plants native to India and Sri Lanka these are widely used for thousands of years in Ayurvedic medicine for the oral treatment of diabetes, Attenuation of postprandial glycemia is hypothesized to reduce the risk of progression from impaired glucose tolerance to diabetes. It is also thought to reduce the number of complications associated with diabetes. A clinical trial conducted to assess the comparison of outcome of marketed drugs and with salacia oblonga, found significant effect on weight and HbA1C value of patients of Type II DM.
FORMULATION AND EVALUATION OF MICROSPHERES OF GLIBENCLAMIDE BY IONOTROPIC GELATION METHOD
Abstract Microspheres is novel drug delivery system for improving therapeutic action of drug, increasing prolong action, lowering dose frequency of dosage form and to improve patient complies. Microspheres are reducing o...
DESIGN AND DEVELOPMENT OF SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM OF LURASIDONE HCl
Objective: Lurasidone HCl is poorly water soluble drug. It should be come in to the BCS Class II drug. Hence oral Bioavailability of Lurasidone HCl is less (9-19%). To develop novel dosage foam of the self-Microemulsifyi...
Pharmacodynamic Studies of Lercanidipine hydrochloride Transdermal Therapeutic Systems
This article reports the assessment of lercanidipine hydrochloride (LH) for transdermal delivery. In-vitro permeation studies were carried out across the porcine ear skin in presence of various penetration enhancers. Pha...
Proteomics Tools for Oral Cancer Biomarker Discovery
Proteomic study of human body fluid (saliva and serum) holds assure as a non-invasive method to identify biomarkers for human oral cancer. The evolving of novel technologies allows researchers to aid the inclusive analys...
“IN-PROCESS QUALITY CONTROL (IPQC): A REVIEW”
All Pharmaceutical Industry aims to make products with good quality products so this can be done by allowing In-Process Quality Control (IPQC) Approaches. The importance of IPQC to carry out complete testing before, afte...