Comparative study between terbinafine and griseofulvin indermatophytosis in children between 5 years to 15 years
Journal Title: IP Indian Journal of Clinical and Experimental Dermatology - Year 2018, Vol 4, Issue 4
Abstract
Introduction Dermatophytosis is a superficial fungal infection of keratinized tissue The infection is known as tinea Various oral and topical antifungal agents used in clinicalpracticeObjective Comparative study between oral terbinafine and griseofulvin in dermatophytosis infection in children between 5 to 15 yearsMethods Patients of both gender and age between 5 to 15 years diagnosed as dermatophytic infection were enrolled for the study Atotal of 100 patientswere divided into two groups One group was treated with oral terbinafine and other withoral griseofulvin for 4 weeks In addition a placebo cream lotion was applied locallyLimitation Large studies are required for more confirmationConclusion Oral terbinafine produced 88 percent cure while cure with griseofulvin was 72 percent Clinical response to oral terbinafine was 16percentbetterNo significant adverse effects were noticed in either groups except in some cases mild gastrointestinal disturbanceKeywords Dermatophytosis Terbinafine Griseofulvin Tinea Fungicidal
Authors and Affiliations
Mrityunjay Kumar Singh, Suraj Bali
Keywords
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- EP ID EP488920
- DOI 10.18231/2581-4729.2018.0063
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