Comparative study of 0.5% bupivacaine and 0.5% levobupivacaine both along with 2% lignocaine in peribulbar block for cataract surgery
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 6
Abstract
Background: Levobupivacaine, the pure S (−) enantiomer of bupivacaine, is strongly emerging as safer alternative along with equal efficacy when compared with its racemic sibling, bupivacaine, for regional anesthesia. Materials and Methods: 100 patients undergoing cataract surgery were randomly allocated in two groups. Group B patients received injection Bupivacaine 0.5% (5mL) + Lignocaine 2% (5mL) + Hyaluronidase (0.1mL) and Group L patients received injection Levobupivacaine 0.5% (5mL) + Lignocaine 2% (5mL) + Hyaluronidase for peribulbar block to provide anesthesia for cataract surgery. We compared hemodynamic parameters, sensory and motor block characteristics and akinesia score between these two groups. Results: Hemodynamic values such as mean arterial blood pressures, heart rate and SPO2 and akinesia scores showed no statistically significant intra group differences during the entire study period. The onset of sensory block in group B was 129.40 ± 15.960 seconds where in group L, it was 130.00 ± 17.613 seconds which was statistically non-significant (p>0.05). The onset of motor block in group B was 180.60 ± 21.325 seconds where in group L, it was 183.80 ± 18.170 seconds which was statistically non-significant (p>0.05). Conclusion: This study has demonstrated that levobupivacaine and bupivacaine are equally successful in achieving clinically satisfactory peribulbar anaesthesia for cataract surgery. Levobupivacaine has a wide therapeutic index so emerging as a safer alternative to bupivacaine for peribulbar block in cataract surgery in elderly population in whom intercurrent diseases are common.
Authors and Affiliations
Dr. Viral G. Trivedi
Keywords
Related Articles
- EP ID EP512077
- DOI -
- Views 94
- Downloads 0
Validating a New Tool on Assessment of Fulfilment of Expectations of Patients with Non-Communicable Diseases – An Ordinal Data Analysis Approach
Introduction: Fulfilment of expectations and attitude to treatment in OPD set-up is an important indicator for quality of service delivery, which is even further important for patients with non-communicable diseases (NCD...
To Study on Hand Hygiene Awareness Among Medical Students In A Teaching Hospital, Rajasthan.
Background- Healthcare-associated infections (HCAIs) are of major concern when it comes to patient safety. Methods- The present study was institution based observational epidemiological study. A total of 100 medical stu...
Clinical and radiographic evaluation of MTA Apexification, Revascularization and Regenerative Endodontics using PRF: A Comparative Study
Introduction: Dental trauma has become more prevalent in the present world owing to increase in spending time outdoors and active participation in sports activities. However, trauma to teeth, especially anterior teeth wh...
Bacteriological Study of Different Water Sources during Outbreaks of Diarrhoea in Ganjam District, Odisha
Background: Water for human consumption must be free from chemical substances and pathogenic microorganisms. Infectious diseases are transmitted primarily through consuming water contaminated with human and animal excret...
Prevalence of Hepatitis B & HCV Infection among Blood Donors of an Apex Hospital – A Retrospective Study
Transmission of blood and blood products is associated with infections like Hepatitis B, Hepatitis C and Human Immunodeficiency Virus. In this retrospective observational study of 22.523 voluntary blood donors at a terti...