Comparative study of 0.5% bupivacaine and 0.5% levobupivacaine both along with 2% lignocaine in peribulbar block for cataract surgery
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 6
Abstract
Background: Levobupivacaine, the pure S (−) enantiomer of bupivacaine, is strongly emerging as safer alternative along with equal efficacy when compared with its racemic sibling, bupivacaine, for regional anesthesia. Materials and Methods: 100 patients undergoing cataract surgery were randomly allocated in two groups. Group B patients received injection Bupivacaine 0.5% (5mL) + Lignocaine 2% (5mL) + Hyaluronidase (0.1mL) and Group L patients received injection Levobupivacaine 0.5% (5mL) + Lignocaine 2% (5mL) + Hyaluronidase for peribulbar block to provide anesthesia for cataract surgery. We compared hemodynamic parameters, sensory and motor block characteristics and akinesia score between these two groups. Results: Hemodynamic values such as mean arterial blood pressures, heart rate and SPO2 and akinesia scores showed no statistically significant intra group differences during the entire study period. The onset of sensory block in group B was 129.40 ± 15.960 seconds where in group L, it was 130.00 ± 17.613 seconds which was statistically non-significant (p>0.05). The onset of motor block in group B was 180.60 ± 21.325 seconds where in group L, it was 183.80 ± 18.170 seconds which was statistically non-significant (p>0.05). Conclusion: This study has demonstrated that levobupivacaine and bupivacaine are equally successful in achieving clinically satisfactory peribulbar anaesthesia for cataract surgery. Levobupivacaine has a wide therapeutic index so emerging as a safer alternative to bupivacaine for peribulbar block in cataract surgery in elderly population in whom intercurrent diseases are common.
Authors and Affiliations
Dr. Viral G. Trivedi
Keywords
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