Comparative Study of Efficacy of Podophyllin Vs 5% Imiquimod in the Treatment of Genital Warts
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 10
Abstract
Introduction: Although genital warts have been documented since the time of Hippocrates, they still remain one of the commonest STDs. This is because the majority are subclinical and no modality of treatment necessarily eradicates warts, maintains clearance, and eliminates the virus. Study was done to evaluate the patients with genital warts, to compare the efficacy of podophyllin, 5% imiquimod, cryotherapy in the treatment of genital warts, to evaluate any adverse reactions occurred due to treatment and to evaluate any recurrences after treatment. Material and methods: Cases of genital warts attending the Department of DVL, osmania general Hospital for a Duration of 20 months from January 2015 to august 2016.Sample size: Total 40 patients, 20 in each group. Results: On comparison of clearance weeks and the treatment given it was observed that there was a significantly higher and early clearance rate with podophyllin p <0.05. There was no significant difference in occurrence of adverse reaction in either of treatment groups statistically (p >0.05).Recurrence was observed in 11.15% cases of podophyllin and there were no recurrence reported in imiquimod group in the present study. Conclusion: According to present study there was a significantly higher and early clearance rate with podophyllin. Clearance of warts with Imiquimod takes long time when compared to podophyllin. Occurance of adverse reactions is almost equal in two groups.recurrence reported in podophyllin but not in IMIQUIMOD group.
Authors and Affiliations
Gurrala Satyanarayan Reddy, B. Mohan Lal, JVDS Prasad, A. Venkata Krishna, K. Radhika Rani, N. Gayatri
Keywords
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