Comparative study of glycoproteins in normal individuals and in patients with hypothyroidism and hyperthyroidism
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 3
Abstract
Aim the present study was carried out to compare the glycoproteins in normal individuals and in patients with hypothyroidism and hyperthyroidismMaterials and Methods This study was carried out at Meenakshi Medical College Research Institute on total 90 individuals 30 hypothyroid patients 30 hyperthyroid patients and 30 normal individuals were taken as controls Each group consisted of both sexes and the participants were between the ages of 25 to 50 years Various parameters like protein bound fucose hexose hexosamine sialic acid and thyroid function test which include ft3 ft4 and TSH were measured in all the 90 individuals The data was collected and analyzedResult Potein bound hexose sialic acid fucose and hexosamine decreased in hypothyroid patients when compared to normal individuals whereas in patients with hyperthyroidism only protein bound hexose and fucose levels increased significantly whereas sialic acid hexose were decreased when compared to normal individualsConclusion Serum Glycoproteins can be additional markers to ft3 ft4 and TSH and aid in diagnosis and management of thyroid disordersKeywords Glycoproteins Thyroid function test Hyperthyroidism Hypothyroidism
Authors and Affiliations
N. Muninathan, P. Mohanalakshmi
Effect of Chemotherapy on Tumor Marker (Ca 15.3) and Serum in Breast Cancer Patients of Southern Eastern Region of Chhattisgarh; 6 Years Follow up Study
Background: At many centers tumor markers are used to detect disease recurrence and to monitor response to chemotherapy therapy in patients with advanced disease, although the real value of serial observation of marker l...
Evaluation of Lipid profile levels in acne vulgaris on low dose isotretinoin: A prospective study
Aim: The present study is to assess the effect on the variations of total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol in patients with acne vulgaris on low dose isotretinoin treatment. Materials and M...
A study to evaluate the vitamin D status in rheumatoid arthritis patients
Introduction: Vitamin D deficiency has been shown to be associated with autoimmune diseases, which is a controversial finding in various previous studies. Moreover there are limited studies done on serum vitamin D and it...
Usefulness of serum gamma glutamyl transferase in assessing severity of preeclampsia
Introduction: Pre-eclampsia is a multisystem disorder, unique to pregnant women after twenty weeks of gestation. In India the incidence of pre-eclampsia is reported to be 8-10% of the pregnancy. It contributes significan...
Study of free radicals (malondialdehyde) in pre-eclampsia and eclampsia in correlation with uric acid and total proteins
Introduction Oxidative stress is a normal phenomenon in normotensive pregnancy however in preeclampsia oxidative stress is exaggerated may result in a greater potential for endothelial oxidative damage It has been report...