COMPARATIVE STUDY OF INTRATHECAL LEVOBUPIVACAINE-FENTANYL AND LEVOBUPIVACAINE IN CAESAREAN DELIVERIES
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 23
Abstract
BACKGROUND The aim of the study is to compare the effects of intrathecal levobupivacaine-fentanyl and levobupivacaine on quality of intrathecal/subarachnoid block and haemodynamic variations in caesarean deliveries. MATERIALS AND METHODS The study was designed as a prospective randomised double-blind study enrolling a total of 60 female patients (age group- 20- 40 years) belonging to ASA grade I and II. The patients were randomly allocated into two groups of 30 patients in each group. The Group-LF received levobupivacaine 10 mg (2 mL) + fentanyl 20 mcg (0.4 mL) and Group-LN received levobupivacaine 10 mg (2 mL) + normal saline (0.4 mL). Characteristics of spinal block, Apgar score, vital parameter variations and complications were recorded. RESULTS In Group LF, onset of action was faster in relation to sensory and motor blockade as compared to Group LN. Two segment regression of sensory block and duration of motor block were prolonged with addition of fentanyl to levobupivacaine. Addition of fentanyl to intrathecal levobupivacaine, prolonged duration of sensory and motor block with faster onset of sensory and motor block with better quality as compared to levobupivacaine. Statistically, no significant difference was observed in mean Apgar score at 1 and 5 minutes. There was no much difference between the groups in relation to haemodynamic variations and complications. CONCLUSION Intrathecal levobupivacaine with fentanyl was found to improve the quality and prolonged duration of intrathecal block. It reduced the need for rescue analgesia/supplementary analgesics for postoperative pain relief without any significant side effects. The levobupivacaine with or without fentanyl maybe used safely for spinal anaesthesia in elective caesarean deliveries.
Authors and Affiliations
Wasudeo Sadashio Barsagde, Naresh Ganapat Tirpude, Kamlesh Sarangdhar Pillewan
A STUDY ON EEG ABNORMALITIES IN CHILDREN WITH MIGRAINE
BACKGROUND Migraine is one of the common causes of headache in children. Migraine and epilepsy are both common episodic neurological disorders. The comorbidity of these two conditions is well known. Many researcher have...
AGE AND SEX RELATED CHANGES ON RR INTERVAL AND ST HEIGHT IN ELECTROCARDIOGRAM (ECG) OF HEALTHY INDIVIDUALS
BACKGROUND AND OBJECTIVES: With advancing age, degenerative changes occur in heart muscle and its conduction system. This study was undertaken to see the ECG changes in different age groups of healthy adults. MATERIALS &...
THORACIC COMPLICATIONS OF OESOPHAGEAL CARCINOMA- A RETROSPECTIVE ANALYSIS OF CT APPEARANCES
BACKGROUND Oesophageal cancer is a common gastrointestinal tract malignancy and Computed Tomography (CT) is generally used for its initial evaluation and staging. Due to the anatomical relationships of the oesophagus, ma...
TUBERCULOUS MASTITIS: A CASE REPORT
As Tuberculosis has come under better medical control in many parts of the world, tuberculosis of breast has been mentioned less frequently as a medical problem in developed countries, but it remains a serious condition...
LIQUID BIOPSY AND ITS CLINICAL APPLICATIONS IN ONCOLOGY
BACKGROUND Liquid biopsy is an ingenious innovative technique which has the potential to provide information about cancers without invasive biopsy, using circulating biomarkers. A progressing cancer features heterogeneit...