Comparative study of intubating conditions after rocuronium bromide and succinylcholine: A randomised controlled double blinded study
Journal Title: Medpulse International Journal of Anesthesiology - Year 2019, Vol 9, Issue 1
Abstract
Background and Aims: Succinylcholine is most commonly used muscle relaxant to facilitate rapid sequence endotrachealintubation. When Succinylcholine is undesirable or contraindicated, we have to use non-depolarizing muscle relaxants forthis purpose1.The Aim of this study was to compare intubation conditions and onset of action after Rocuronium bromide and Succinylcholine following induction with Sodium thiopentone as a sole anaesthetic agent in elective otherwise healthy adult population. Materials and Methods: Eighty adult patients undergoing elective surgery, requiring general anaesthesia were selected and divided randomly in to group A and group B. Group A patients given Inj. Rocuronium Bromide 0.6 mg/kg and group B patientsgiven Inj .Succinylcholine 1.5 mg/kg after induction with Inj. Sodium thiopentone. Intubating conditions were assessed using scoring system based on criteria of cooper et al.2Time of intubation was recorded as onset of action of muscle relaxant.. Hemodynamic were recorded preoperatively, after muscle relaxant, after intubation, 5 min, 10 min 15 min after intubation. Results: Intubating conditions were excellent in 37 patients in and good in 3 patients in group A and excellent in all 40 patients in group B.Onset of action was 60-90 secs in group A and 60 secs in group B. Hemodynamic changes were comparable in both groups. Pulse rate, systolic and diastolic blood pressure were increased after intubation but reached baseline value within 5 mins. Conclusion: Rocuronium bromide is new non depolarizing muscle relaxant which can be used as an alternative to Succinylcholine for rapid sequence induction as it has rapid onset of action as compared to other non depolarising muscle relaxants.
Authors and Affiliations
Kanvee M Vania, Vandana S Parmar
Keywords
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