Comparative Study of Pressor Response to Laryngoscopy and Intubation with Oral Spray of Nitroglycerine and Oropharyngeal Spray of Lignocaine
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: The objective is to compare the efficacy of oral nitroglycerin spray and oropharyngeal lignocaine spray in attenuating the hemodynamic responses to laryngoscopy and intubation. To evaluate the efficacy of 0.8mg of oral nitroglycerin spray and 100mg of 10% of oropharyngeal spray of lignocaine with their associated side effects. After obtaining ethical committee clearance, 60 patients were divided into two groups of 30 each. Group L - Lignocaine group (n=30) - received oropharyngeal Lignocaine 10% spray 100 mg 3 minutes before induction. Group N - Nitroglycerin group (n=30) - received oral nitroglycerin spray 0.8mg 30 seconds before induction. Heart rate, systolic and diastolic blood pressure were recorded at baseline, at induction, 1, 3, 5 and 10 minute intervals after laryngoscopy. NTG spray decreases SBP and DBP more effectively as compared to lignocaine group following laryngoscopy and intubation. The lignocaine group had an increase in mean arterial pressure and the NGT group had a decrease in mean arterial pressure.Nitroglycerine oral spray in the dose of 0.8 mg, given 30 seconds before induction can be a better alternative in attenuating the haemodynamic responses to laryngoscopy and intubation. Keywords:Lignocaine, Nitroglycerin, haemodynamic changes, laryngoscopy
Authors and Affiliations
V. Madhuri Gopal
Keywords
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