Comparative Study of Rocuronium And Succinylcholine For Rapid Sequence Induction Of Anaesthesia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
Introduction: Succinylcholine chloride remains Gold standard neuromuscular blocking drug in providing ideal intubating conditions in Rapid sequence intubation. Rocuronium bromide is the only drug currently available which has the rapidity of onset of action like succinylcholine chloride. Hence the present study was undertaken to compare rocuronium bromide with succinylcholine chloride for use during rapid sequence intubation in adult patients. Results: It was noted that succinylcholine chloride 1.5 mg kg-1 body weight produced excellent intubating conditions in 96.67% patients. Rocuronium bromide 0.6 mg kg-1 body weight produced excellent intubating conditions in 60% of patients but produced good intubating conditions in 36.67% of patients. Rocuronium bromide 0.9 mg kg-1 body weight produced excellent intubating conditions in 93.33% of patients, which was comparable to that of succinylcholine chloride. Thus increasing the dose of rocuronium bromide increased the number of excellent intubating conditions but at the cost of increased duration of action. Conclusion: Thus, from the present study, it is clear that succinylcholine chloride is the drug of choice for rapid sequence intubation. Rocuronium bromide is a safe alternative to succinylcholine chloride in conditions where succinylcholine chloride is contraindicated and in whom there is no anticipated difficult airway.
Authors and Affiliations
Dr. Bommisetty Trinath Kumar, Dr. Balleda Sandhya
Keywords
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- EP ID EP395412
- DOI 10.9790/0853-1709080513.
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