Cytological evaluation of false negative rate in thyroid: an institutional experience
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12
Abstract
Background: FNAC is a simple, safe, cost effective diagnostic procedure that provides rapid diagnosis in evaluation of thyroid lesions. Aim: The aim of this study was to analyse false negatives and false positives in palpable thyroid nodules Materials and methods: A two-year prospective study was done in department of pathology Gitam institute of medical sciences and research. During the study period 99 aspirations were done, on aspiration lesions were grouped into three categories. Histopathological correlation was possible only in 35 cases. Results: Cytohistopathological correlation for nodular goitre was 48.5%. false negative rate was 31.4%, false positive rate was 5.7%. Conclusion: It is difficult to differentiate between nodular goitre and follicular neoplasm on FNAC due to cytomorphologic similarities. FNAC results must be interpreted in combination with radiological and histopathological findings.
Authors and Affiliations
Vasundara. Gardas, Prasanthi. C, K. V. Murali Mohan
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