Prospective Study to Identify Commonest Organisms and Antibiotic Sensitivity in Peritonitis Due to Duodenal Ulcer Perforation in Govt. Rajaji Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Perforative peritonitis is one of the most commonly encountered surgical acute abdominal emergencies in surgery casuality. The importance of this study is to reduce the postoperative complications like septicemia, wound infection, burst abdomen, bronchopneumonia, long hospital stay etc., by identifying the inciting organisms and its sensitive antibiotics rather than using empirical antibiotic therapy which is followed at present, in immediate postoperative period. Among hollow viscus perforations duodenal perforation is the most common site. The organisms setting up the peritonitis features are diverse according to the location of perforation. The common organisms isolated in proximal bowel perforation are E.coli, klebsiella, lactobacilli, streptococci, candida. There is an increasing trend in isolating anaerobic organisms or polymicrobial isolates as the perforation occurs distally and the time interval between the disease onset and time of intervention increases. Majority of rural patients present in surgical opd lately. Also there is a direct relation between interval of disease onset & time of intervention and postoperative morbidity. In proximal bowel perforation, proposed antibiotic coverage is against gram positive cocci and gram negative enteric organisms. Hence administration of appropriate antibiotics in immediate postoperative period reduces poor postoperative outcome.
Authors and Affiliations
Dr. C. Gangalaksmi, Dr. R. Tennison Post Graduate, Department of General Surgery, Madurai Medical College, Madurai, Tamilnadu, India.
Keywords
Related Articles
- EP ID EP596023
- DOI 10.9790/0853-1603063843
- Views 78
- Downloads 0
Study of Serum Adenosine Deaminase and Transaminases in type 2 Diabetes Mellitus
Adenosine deaminase (ADA) is an enzyme present in most human tissues. It is also known as adenosine aminohydrolase and involved in purine metabolism. It is an important marker of inflammation. Elevation of the main serum...
A Comparative Study on Safety, Efficacy, and Cost of Glipizide versus Glimepiride as an Add-On Therapy to Metformin
Background: Diabetes Mellitus (DM) is associated with abnormalities in carbohydrate, fat, and protein metabolism. Pharmacoeconomic studies are pertinent to the decision-making process when trying to balance the costs of...
Study of Serum C-Reactive Protein In Acute Ischemic Stroke And Its Impact on Stroke Severity And Prognosis.
Introduction:Acute ischemic stroke (AIS) has several risk factors; atherosclerosis of vessels is the most important one. Atherosclerosis being an inflammatory condition is associated with raised serum level of CRP. Hence...
Diagnostic delay of oral squamous cell carcinoma in a cohort of Bulgarian patients
Oral squamous cell carcinoma is the most common malignancy of the oral cavity. Although oral cancers are usually visible and accessible, delays in diagnosis are not uncommon. The aim of the present study was to character...
Stone Expulsion Rate of Small Distal Ureteric Calculus Could Be Predicted With Serum C-Reactive Protein, White Cell Counts And Neutrophil Percentage: A Prospective Study
Purpose:To determine the relationship between stone expulsion rate of distal ureteric calculus less than or equal to 10mm in size and C reactive protein (CRP) level, white cell count and neutrophil percentage. Materials...