Comparative Study of Ropivacaine and Levobupivacaine given Paravertebrally in Breast Cancer Surgeries
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Background: “Pain” an unpleasant sensory and emotional experience associated with any surgery. In modern medicine, pain control is the standard of care and right of a patient. Providing post-operative analgesia to the patient gives subjective comfort which helps in restoring the altered physiology and immunological response. Aim: To assess the efficacy of injection ropivacaine with fentanyl and injection levobupivacaine with fentanyl given paravertebrally for providing intraoperative and post-operative analgesia in elective surgeries for breast cancer patients. Study Design: Prospective randomized double blind study. Materials and Methods: Our study included 90 patients aged between 18 and 60 years of ASA Grade I and II scheduled for elective breast cancer surgeries. Group A received general anesthesia (GA) along with injection ropivacaine 0.25% (0.3 ml/kg) with injection fentanyl 25 mcg in thoracic paravertebral space. Group B received GA along with injection levobupivacaine 0.25% (0.3 ml/kg) with injection fentanyl 25 mcg in thoracic paravertebral space. Group C received GA alone. For assessing the intraoperative hemodynamic stability and post-operative analgesia, various parameters were recorded. Results: The result of our study demonstrated that thoracic paravertebral block (PVB) led to superior intraoperative hemodynamic stability and post-operative analgesia of higher degree when compared with GA alone in a patient undergoing breast cancer surgeries. Thoracic PVB with both A and B Groups produced comparable analgesia. Conclusion: It was concluded that injection ropivacaine and injection levobupivacaine with fentanyl as an additive given paravertebrally during breast cancer surgeries under GA provides equal and effective hemodynamic stability and satisfactory post-operative analgesia of the same duration and substantially less incidence of any post-operative complication such as nausea and vomiting with reduced post-operative stay.
Authors and Affiliations
Raghvendra Upadhyay, Rajan B Godwin, Mayura Setiya
Keywords
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