Comparative Study of Sevoflurane and Sodium Thiopentone in Electroconvulsive Therapy

Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 4

Abstract

Sodium thiopentone is most commonly used agent for electroconvulsive therapy (ECT) in India, but have side effects like prolonged awakening time, arrhythmias and laryngeal spasm. Therefore keeping into view the requirements of ideal and safe induction agent for anaesthesia in ECT, new modality of induction agent like sevoflurane have been tried. This is a randomised prospective crossover study to compare recovery profile and hemodynamics of Sevoflurane and Thiopentone sodium. 100 patients who underwent ECT were divided into two groups Group-T & Group S. Group-T patients were induced with Inj. sodium thiopentone and inj.succinyl choline. In group-S, induction was done with Sevoflurane 8%. After loss of eye lash reflex inspired sevoflurane concentration was reduced to 2% and inj. succinyl choline 0.5 mg/kg was administered intravenously. Onset of action, seizure duration, recovery time, hemodynamic effects and side effects were noted. Power of study was 80% and p-value <0.05 was considered significant. All data were represented as mean ± SD. The seizure duration was shorter in group S compared to Group T. The rise in heart rate (HR) was significantly more in group T as compared with group S. The rise in mean blood pressure (MBP) after delivering ECT was more in group S as compared with group T. The mean time of eye opening and response to verbal command was shorter in group S (p=0.0129, p=0.0356 respectively) than group T. Conclusions: Sevoflurane induction was well tolerated by our patients, and its induction was associated with faster recovery. Sevoflurane does not compromise seizure induction and may offer a stable heart rate

Authors and Affiliations

Dr Chetna Jadeja

Keywords

Related Articles

Feasibility of Calot’s Triangle Dissection Outcome as Easy versus Difficult Laparoscopic Cholecystectomy Based on Clinico radiological Assessment

Laparoscopic cholecystectomy (LC) is the gold standard treatment for symptomatic cholelithiasis. However conversion is inevitable in difficult cases among all laparoscopic cholecystectomies 1-13% requires conversion to o...

Evaluation of Peak Expiratory Flow Rate in Tea Garden Factory Workers in Dibrugarh District, Assam

Introduction: Tea which is brewed from the tea plant Camellia sinensis is an indispensable beverage used the world over. Manufacture of black tea involves several labour–intensive processes: sifting and blending being th...

Neonate presenting with Polydactyly - Think of Ellis Van Creveld Syndrome

Ellis-van Creveld syndrome (EVCS) or meso/chondroectodermal dysplasia is a rare congenital, autosomal recessive disorder. It is caused by mutation of EVC gene (both EVC1 and EVC2) on locus 4p16. The incidence of EVCS in...

Isokinetic Shoulder Torque Development in Children Six through Twelve Years Old

Muscle strength is necessary for optimal posture and efficient movement to occur. It enables individuals to perform everyday activities without undue fatigue. The purpose of this study was to establish a reference data o...

A Review on Restless Legs Syndrome and its Management

Restless Legs Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological sensorimotor disorder which is characterized by uncontrollable urge to move legs which is accompanied by painful sensation. RLS can be d...

Download PDF file
  • EP ID EP205669
  • DOI -
  • Views 141
  • Downloads 0

How To Cite

Dr Chetna Jadeja (2014). Comparative Study of Sevoflurane and Sodium Thiopentone in Electroconvulsive Therapy. Journal of Medical Science And clinical Research, 2(4), 628-632. https://europub.co.uk/articles/-A-205669