Comparative Study of Significance of Lipid Profile, Platelet Count and MPV-Diabetics and Non-Diabetics
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 5
Abstract
Diabetes mellitus is a global pandemic and is a complex disease characterized by chronic hyperglycaemia, metabolic abnormalities and long term macro – vascular and microvascular abnormalities involving major organs. Platelet parameters such as high platelet count and mainly high Mean Platelet Volume (MPV) have been reported in diabetic patients, contributing to the increased risk of vascular disease. Its relation to lipid profile has also been documented in literature. The objective of our study is to compare the simple variables of platelet count, MPV, and lipid profiles in normoglycemics and in diabetics. This cross sectional study was conducted at Sapthagri Institute of Medical Sciences and Research Center, Bangalore, India between the periods of December 2013 to March 2104. A total of 100 cases were included with 50 being diabetics and other 50 being non – diabetics. The study documented a significant increase in total cholesterol and LDL (females>males) in diabetics. Triglycerides and VLDL (males>females) in were more in diabetics compared to the normoglycemics. Platelet count has increased more significantly in diabetic females than males and control group.MPV has increased more significantly in diabetic males than females and control group. Simple parameters like above can be used to screen patients at high risk for complications, aiding in better patient care. Keywords: Diabetes, Platelet count, Lipid profile, MPV (Mean Platelet Volume), Microvascular
Authors and Affiliations
Vijaya C, Archana Shetty, Dr. Parikshith
Keywords
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