Comparative Study of Thiopentone & Etomidate For Pressor Response in Hypertensive Patients Posted For Elective Surgeries
Journal Title: PARIPEX-Indian Journal of Research - Year 2015, Vol 4, Issue 6
Abstract
Background & objective:. The present study aims at comparing the hemodynamic effects of thiopentone and etomidate during induction in hypertensive patients and also to assess any untoward side effects of either drug. Methods:This study was conducted among 60 patients in the age group of 18 – 75 yrs undergoing various elective laminectomy and orthopeadic procedures. They were divided into 2 groups of 30 each. General anaesthesia was induced in Group E with Inj.etomidate 0.3mg/kg and in Group T with Inj. Thiopentone 5mg/kg. Inducing agent has been given over a period of 60 seconds in all the patients. Inj. Vecuronium bromide (0.1mg /kg. body wt.), was injected after loss of eye lash reflex in both groups. Nitrous oxide and oxygen was used for mask ventilation in both study groups. Subsequently, heart rate, SBP, DBP, MAP and ECG changes were recorded at one, two and three minutes after induction . Results : It has been observed that there is no clinically significant difference between in hemodynamic parameters (HR, SBP, DBP and MAP) following induction with etomidate and thiopentone. Conclusion: From our study, it has been concluded that there is no significant difference regarding hemodynamic parameters following induction with thiopentone and etomidate in adult hypertensive patients posted for elective surgery.
Authors and Affiliations
DR. R. KONDA REDDY, DR. K. ANITHA, DR. R. CHANDANA
Keywords
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