Comparative Study on Umbilical Cord Blood Lipid Profile in Normal and Low Birth Weight Neonates
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 7
Abstract
Abstract:Altered lipid levels are the recognized factors to cardiovascular disease in adults.This process is considered to begin in early life and progress silently over decades.An increase in low-density lipoprotein cholesterol (LDL-C) and decrease in high-density lipoprotein cholesterol (HDL-C) levels are associated with the atherosclerotic process, with its prodromal stages starting in early life.Objective of study to compare umbilical cord blood lipid profile between normal and low birth weight neonates.This was a cross sectional study carried out at neonatal Units of Department of Pediatrics, SMS Medical College, Jaipur from April 2015 to March 2016 included 110 babies each group of normal and low birth weight babies.Statistically significant difference ( P =< 0.001) was found between the mean TG and mean VLDL levels among the normal( TG = 641.61±18.05 mg/dl,VLDL =8.27±3.59mg/dl)and low birth weight babies( TG=60.44±36.63 mg/dl,VLDL = 12.72±8.95 mg/dl). No statistically significant difference was found between the mean values of TC, LDL and HDL among normal (TC=96.04±24.33mg/dl, LDL=64.71±21.02 mg/dl, HDL=23.05±7.043mg/dl) and low birth weight babies(TC=103.30±33.65mg/dl,LDL==67.22±30.93mg/dl,HDL=23.51±7.78mg/dl).Lipid (all types) levels were higher in LBW babies as compared to normal birth weight babies but the difference was statistically significant for TG and VLDL. Keywords:SGA, AGA, TG, VLDL.
Authors and Affiliations
Anamika Gora, Palak gupta, M. L. Gupta
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