Relationship between Lipid Profile and Left Ventricular Mass in Obese Adolescents
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 6
Abstract
Childhood obesity is associated with an increased risk of death due to cardiomyopathy and atherosclerosis in adulthood. Hyperlipidemia, hypertension, obesity, diabetes mellitus, smoking, lack of exercise, and family history of cardiovascular disease is closely associated with cardiovascular process. Dyslipidemia is one of the complications of obesity. It is known that an increase of LDL, decreased HDL is associated with atherosclerosis, which indirectly leads to an increase in left ventricular mass.Examination by M-mode echocardiography is needed to obtain a picture of the left ventricular mass and left ventricular function in a child with obesity. Echocardiography can be a reliable andnon-invasive indicator for the existence of left ventricular hypertrophy. The objective of the study was to determine the relationship between lipid profile and left ventricular mass in adolescent with obesity. It was an analytic observational study using cross sectional method on 40 obese adolescents and 40 non-obese adolescents aged 13-18 years from August 2013 to February 2014. The data included anthropometry size in obese and non-obese adolescents, lipid profile levels of total cholesterol, high-density lipoprotein (HDL), low density lipoprotein (LDL) and triglycerides and left ventricular mass were measured using echocardiography. Data was analyzed by Pearson correlation and processed by program Statistical Product and Service Solutions (SPSS) version 22. There is a very significant different of total cholesterol, LDL, andtriglycerides levels in obese and non-obese adolescents (p <0.001), similarly obtained left ventricular mass, but no significant different in HDL cholesterol (P = 0.127). No significant association was found between total cholesterol levels (r = -0.22, p = 0.86), LDL (r = -0.163, p = 0.16), HDL (r = -0.253, p = 0.06) and triglycerides (r = -0.132, p = 0.21) with left ventricular mass in obese adolescents.There is a very significant different of total cholesterol, LDL, and triglycerides levels in obese and non-obese adolescents, similarly obtained left ventricular mass, but no significant different in HDL cholesterol. Lipid profile is not related to left ventricular mass in obese adolescents. Keywords: lipid profile, left ventricle mass, obesity.
Authors and Affiliations
Erling David Kaunang, Suryani As’ad, Sarah M. Warouw, Peter Kabo
Keywords
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