Comparison between Cabergoline and Coasting in Prevention of Ovarian Hyperstimulation Syndrome and their effect on Intracytoplasmic Sperm Injection Outcome
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 73, Issue 1
Abstract
<strong><span lang="EN-US">Aim of the work: </span></strong><span lang="EN-US">ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, serious and potentially fatal complication of ovarian stimulation, affecting1–14% of all IVF/ICSI cycles. This study aimed to compare cabergoline after hCG administration with delayed hCG administration (coasting) in high risk patients to prevent OHSS in ART cycles. <strong>Patients and methods:</strong> this prospective comparative randomized study included 100 patients at risk of OHSS performed in the Assisted Reproductive Technologies Center, Al-Azhar University and in Private IVF Centers during the period from November, 2015 to October, 2016. <strong>Results:</strong> comparison between the two groups showed no significant difference regarding age, BMI, presence of risk factors of OHSS, but there was a significant difference regarding FSH, LH and the mean diameter of follicles on day of hCG administration.<strong> Conclusion: </strong>PCOS affects 5 to 10% of women of childbearing age and is the most common cause of anovulatory infertility in developed countries. <strong>Recommendations: </strong>further studies including large number of cases and for longer duration will further confirm the efficacy of cabergoline and coasting on prevention of OHSS.</span>
Authors and Affiliations
Eman Helal
Keywords
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- EP ID EP584399
- DOI 10.12816/ejhm.2018.11877
- Views 133
- Downloads 0
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