Comparison of AngioJet thrombectomy system and catheter-directed thrombolysis in treatment of acute lower extremity deep venous thrombosis
Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 10
Abstract
"Objective To investigate the treating effects of acute deep venous thrombosis (ADVT) of lower extremity using the AngioJet thrombectomy system compared to catheter-directed thrombolysis (CDT). Methods A total of 30 ADVT patients admitted to Baogang Hospital of Inner Mongolia from January 2020 to March 2021 were selected, and randomly divided into control group (n=15) and observation group (n=15). The control group received CDT treatment, while the observation group underwent treatment with the AngioJet thrombectomy system. The treatment outcomes between the two groups were compared. Results The thrombus removal grade in the observation group was better than that in the control group (Z=2.340, P=0.019), with a limb swelling reduction rate of 93.33% versus 53.33%, respectively, showing a statistically significant difference (P＜0.05). The thrombolytic time ［(0.50±0.11)h vs (72.14±0.42)h, P＜0.01］ and the amount of urokinase used ［(18.51±2.02) ×10<sup>4</sup> u vs (85.34±2.75) ×10<sup>4</sup> u, P＜0.01］ were both lower in the observation group compared to the control group. The incidence of complications in the observation group (13.33%) was slightly lower than that in the control group (26.67%), but the difference was not statistically significant (P＞0.05). Conclusion The AngioJet thrombectomy system offers better effects for ADVT patients compared to CDT, with shorter thrombolytic time, less urokinase usage, and a better clinical safety profile."
Authors and Affiliations
WANG Junjie, HAN Bo
Keywords
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