Comparison of CT only contour with MRI guided contouring in external beam radiotherapy for carcinoma rectum
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 10
Abstract
Aim:The purpose of the study is to compare CT only contour with MRI guided contour for delineation of the gross tumour volume (GTV) in carcinoma of rectum in external beam radiotherapy.Materials and Methods:18patients who underwent external beam radiotherapy treatment for carcinoma rectum were selected retrospectively. For all the patients, both CT and MRI were done as a part of planning process. Two sets of GTV were generated using only CT and with MRI assistance by a single oncologist. The generated contours were then compared and quantitatively analyzed using volume analysis and dice index.Results:The CT mean GTV was larger than the MRI mean GTV volume (68.54 ± 17.56 cc for CT versus 80.95 ± 19.19 cc for MRI). The dice index value between CT only GTV and MRI assisted GTV was 0.71 ± 0.13. The comparison of GTVs showed that the GTV_MRI was comparatively small and inside the GTV_CT except for six patients for whom GTV_MRI was marginally outside the GTV_CT.Conclusion:The study showed that using MRI guidance for GTV delineation in carcinoma rectum is preferable and more accurate as compared to CT-only imaging because of superior soft tissue contrast.
Authors and Affiliations
Sudha Rani, Katta Charu Goutham
Keywords
Related Articles
- EP ID EP276380
- DOI 10.17511/ijmrr. 2017.i10.07
- Views 133
- Downloads 0
Study of clinical risk factors and predictors of post stroke vascular cognitive impairment
Introduction: Cognitiveimpairment due to cerebrovascular disease is termed” vascular cognitive Impairment “(VCI) and forms a spectrum that includes vascular dementia and milder forms of cognitive impairment. Vascular cog...
Pinch test: a reliable physical sign for management of acute appendicitis
Introduction: Acute appendicitis is often a surgical emergency. It primarily affects the growing children and needs to be evaluated early. Many patients of acute appendicitis will respond to antibiotics therapy. But a nu...
Role of vitamin B supplementation with Fluoxetine in treatment of depression: A randomized controlled clinical trial
Objective: To explore the change in antidepressant efficacy of Fluoxetine with vitamin B supplementation. Methods : The present study is a Single Centre, Open Label, Active Controlled, Parallel, and Single Period 8- Week...
Biomedical waste management at tertiary level hospital–Rajindra Hospital [Government Medical College], Patiala-A situational analysis
Background: Studies in India and other developing countries has shown poor practice of Biomedical waste management [BMW]. Hence this study was undertaken to situation of BMW in our hospital, to identify the gaps and to t...
High Sensitivity C-Reactive Protein an inflammatory marker and lipoprotein levels in patients with coronary heart disease
Background: C-Reactive Protein is a good marker of systemic inflammation which can be measured easily. Atherosclerosis lesions are intimal thickening of arteries. Inflammatory and immune cells constitute an important par...