Comparison of Dexmedetomidine and Magnesium Sulphate to assess neuroendocrine response using blood glucose as a marker in laparoscopic Cholecystectomy
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Anaesthesia and surgery induced stress response can be modulated by premedication drugs.This study was done to assess the extent of stress attenuation by using dexmedetomidine and magnesium sulphate premedication by analyzing perioperative variation in bloodglucose level during laparoscopic cholecystectomy under general anaesthesia.In a prospective blind study,90 ASA1 patients who were posted for elective laparosopic cholecystectomy under general anaesthesia were divided into three groups .Group D patients (n =30) were given intravenous dexmedetomidine 1μgm/kg , Group M patients (n =30) received magnesium sulphate 30mgm/kg ,Group C patients (n =30) were given normal saline over a 10 min period ,before induction of anaesthesia.Hemodynamic parameters like heartrate,MAP were assessed. Anaesthesia and surgical techniques were standardized.Peroperative blood glucose values were assessed preoperatively, 30 min and 1 hour after beginning of surgery.Both premedicants attenuated hemodynamic and neuroendocrine stress response of pneumoperitoneum and general anaesthesia.The dexmedetomidine group showed better intraoperative stability and blood glucose control on comparison to magnesium sulphate group.During laparoscopic cholecystectomy,dexmedetomidine and magnesium sulphate have effectively modulated neuroendocrine stress response of general anaesthesia as analyzed by blood glucose variation, but dexmedetomidine was better
Authors and Affiliations
Vairavarajan Chandrasekaran, Prathima Sharon Jayaraj
Keywords
Related Articles
- EP ID EP239287
- DOI 10.9790/0853-1610037780
- Views 113
- Downloads 0
Magnitude and Pattern of Disease Presentation among Students in Federal University of Technology Owerri Nigeria
Students’ wellbeing is paramount to their effective participation in academic and extracurricular activities. This study described the prevalence and pattern of disease presentation among students attending Federal Unive...
Spot Urine Protein: Creatinine Ratio as Risk Factor in Relapsing Nephrotic Syndrome
Background: Nephrotic Syndrome is a common childhood illness. Major problem with this disease is frequent relapse. So, it is important to identify the children at risk for relapses to treat and further follow up. Aim &Ob...
Prevalence of dental and maxillofacial developmental and acquired diseases on panoramic radiographs among Jeddah population, Saudi Arabia
Panoramic radiographs are the mostly used for screening of teeth and maxillofacial bones for detecting diseases and abnormality as well as their extension and localization in relation to adjacent structures. This retrosp...
Bacteriological profile and Antimicrobial resistance in Neonatal Septicemia
Septicemia remains significant cause of morbidity and mortality in the newborns, more so in the developing countries. Reports of multi resistant bacteria causing neonatal sepsis in developing countries are increasing. Th...
3dcephalometric Norms With new CBCT Imaging Protocol
.