Comparison of Dexmedetomidine – Propofol and Clonidine – Propofol for ease of Insertion of Laryngeal Mask Airway

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 6

Abstract

Abstract: It is a common practice to use a Laryngeal mask for administration of anaesthetic and ventilation gases to patients. It has advantages over endotracheal tubes which are longer and seal the trachea below the vocal folds. However sometimes laryngeal mask airways can cause trauma to laryngeal walls. The aim is to compare the efficacy of Dexmedetomidine – Propofol combination and Clonidine – Propofol combination for LMAinsertion in terms of Ease of insertion and Haemodynamic responses to LMA insertion. The study was conducted in MGM Hospital 60 patients aged between 20 and 50 years belonging to ASA I-II category with MPG grade I and II who were scheduled for short elective surgeries. Patients were divided into 2 groups randomly: Dp (Dexmedetomidine) or Cp (Clonidine) with 30 patients in each group. After pre-oxygenation for 3 minutes with 100% O2 on mask, group Dp received 1µg/kg dexmedetomidine and group Cp received 1µg/kg of Clonidine diluted in 10ml normal saline respectively, i.v over 10 minutes. Thirty seconds later, patients were induced with intravenous injection of propofol 2.5mg/kg mixed with 1 ml of 2% lignocaine. 90 sec after propofol bolus, first attempt at insertion of LMA was made. If required, further increments of propofol 0.5mg/kg I.V were given every 30 seconds till loss of consciousness and loss of eyelash reflex. After insertion, cuff was inflated with recommended volume of air, and patient connected to breathing circuit. On comparing Post LMA, 1 min, 2mins, 3 mins mean heart rate to Pre LMA mean heart rate, in dexmedetomidine group there was not statistically significant difference (p > 0.05). We found a statistically better jaw relaxation in dexmedetomidine group compared toClonidine group. No patient in dexmedetomidine group had coughing but 6 patients (20%) had grade 2 of coughing and 1 patient (3.33%) had grade 4 of coughing in Clonidine group. 1 patient (3.33%) required two attempts at LMA insertion in dexmedetomidine group and 5 patients (16.67%) in Clonidine group required two attempts at LMA insertion. There was no statistically significant difference between the respiratory rates between both the groups. From our study we came to a conclusion that dexmedetomidine gives better insertionconditions and better attenuation of pressor response to LMA insertion compared to Clonidine in the given doses and that dexmedetomidine can be used with an advantage for LMA insertions in short surgical procedures. Keywords:Dexmedetomidine/Propofol, Clonidine/Propofol, Insertion of Laryngeal Mask Airway.

Authors and Affiliations

Shanthan Kumar Repalle, Rakam Kalyan

Keywords

Related Articles

Study of breastfeeding practices amongst PNC mothers in urban slum areas in Solapur city, Maharashtra

Since 1993, WHO’s effort to improve infant and young child nutrition have focused on promoting breastfeeding. It is estimated that suboptimal breastfeeding especially non-exclusive in first six months of life results in...

Are Rheumatoid Arthritis Patients More Vulnerable To Cardiovascular Disease?

Increased mortality rate because of Cardiovascular Disease [CVD] is well established in Rheumatoid Arthritis [RA] patients. We have estimated the role of serum malondialdehyde [MDA] and homocysteine levels of serum in R...

MRI Evaluation of Legg Calve’ Perthes Disease – A Preliminary Study

Abstract: Legg-Calvé-Perthes disease is a common cause of hip pain in preadolescent children that may be initially clinically and radiographically difficult to diagnose and stage. Till recently, diagnosis and treatment d...

Comparative Study Para Sympathetic Nerve Function Test In Normal and Moderately Hypertensive Patients

Abstract: Hypertension involves almost all the systems of body, predominantly affecting ANS which controls involuntary aspects of body functions. When CVS is affected, it may lead to myocardial infarction, and cardiac fa...

Significance of antioxidants in human health

Abstract: From the last few years, there has been a great attention towards the field of free radical chemistry for health point of view. Free radicals reactive oxygen species and reactive nitrogen species are generated...

Download PDF file
  • EP ID EP373063
  • DOI -
  • Views 77
  • Downloads 0

How To Cite

Shanthan Kumar Repalle, Rakam Kalyan (2017). Comparison of Dexmedetomidine – Propofol and Clonidine – Propofol for ease of Insertion of Laryngeal Mask Airway. Scholars Journal of Applied Medical Sciences, 5(6), 2154-2159. https://europub.co.uk/articles/-A-373063