Comparison of effect of aspartame (artificial sweetener) and aspartame-sweetened diet drink on autonomic reactivity of volunteers
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 7
Abstract
Background: Obesity is the single most important risk factor in the onset of various diseases. Dieting is considered as an important part of today’s daily life; the aim of our study is to explore the effects of aspartame on autonomic reactivity and compare it with the effects of aspartame-sweetened diet drink in human volunteers. Aim and Objectives: To study and compare the effect of aspartame and aspartame-sweetened diet drink on autonomic reactivity. Materials and Methods: This is a comparative study done in the department of physiology. After getting an Institutional Ethical Committee clearance and explained informed and written consent from all the participants. The study duration was for 2 months and the study population was 120 volunteers of age 20–30 years of both genders were randomly chosen and included in the study. They were divided randomly as 80 volunteers in the study group and 40 in the control group. The study Group A in whom aspartame (artificial sweetener) diluted in water was given. Group B in whom diet drink was given and Group C as controls who was fed with plain water and tested for various parameters of autonomic reactivity. Results: The findings in our study showed increased sympathetic activity after consumption of aspartame diluted in water and also showed further increased sympathetic activity in subjects who consumed aspartame-sweetened diet drink than the controls. Conclusion: Aspartame is causing various health hazardous to humans, it is no safer to consume aspartame as a sugar substitute.
Authors and Affiliations
Kanietha Priya A S, Ganesh Prasath S
Association of nutritional anemia with leukocyte and platelet counts in people of Odisha
Background: Anemia is the most common hematological disorder in the world, due to deficiency of micronutrients such as iron, Zn, Se, Cu, folic acid, and vitamins. Iron deficiency impairs immune response and bactericidal...
A study to evaluate the behavioral dimensions of “Nomophobia” and attitude toward smartphone usage among medical students in Bengaluru
Background: Smartphones have become the most popular electronic gadgets in India and student communities across the country have been in awe of these devices. Medical students have found profound applications of smartpho...
Effects of chronic ingestion of Bisphenol A on gut contractility in rats
Background: Bisphenol A (BPA) is a plastic toxin widely used in manufacturing of plastic containers. It is known to produce a variety of toxic effects on body functions including reproduction, metabolism, and development...
Impact of type 2 diabetes mellitus on short term and working memory
Background: The increase in diabetes among the elderly is of concern because in addition to the wide range of traditional diabetes complications; evidence has been growing that diabetes is associated with increased risk...
Vitamin D deficiency among female students of a Government Medical College
Background: Vitamin D deficiency is an unrecognized epidemic in many populations. Aims and Objectives: This study aims to assess the levels of Vitamin D among female medical students. Materials and Methods: A total of 10...