A prospective observational study of use of antibiotics at emergency department in tertiary care hospital

Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 1

Abstract

Background: Antibiotics are most extensively used drugs in hospitals. It is documented that antibiotics in developing countries have been consumed in relatively high levels, and consequently, led to higher occurrence of improper use and greater levels of resistance when compared to developed countries. Aims and Objective: The aim of this study was to analyze the antibiotic prescription patterns in emergency department (ED) prescribed for various illnesses. Materials and Methods: The prospective observational study was done by analyzing prescriptions in ED for 48 h of admission in tertiary care hospital, Mysore. The number of drugs and antibiotics prescribed were recorded. Based on this data, the WHO prescribing indicators were analyzed. Results: In our study, we found a total of 1009 drugs, and 186 antibiotics were prescribed in the 150 patients studied, that is, an average of 6.73 drugs/prescription and 1.24 antibiotics/ prescription. The common diagnoses were organophosphate poisoning (19.3%), multi-organ failure/septic shock (13.3%), and cerebrovascular accidents (12%). 88% of antibiotics were prescribed from the essential drugs formulary list and 47% of the prescriptions included the drug’s generic name. Cephalosporins (54.3%) were the most commonly prescribed antibiotic. Conclusion: The study reveals that practice toward polypharmacy and antibiotic prescribing was frequent in ED. Hence, there is a strong need for guidelines and protocol for the use of antibiotics in ED.

Authors and Affiliations

Mamatha V, Nagesh HN, Parashivamurthy BM

Keywords

Related Articles

Oxaliplatin-induced laryngospasm - A case report

Oxaliplatin is third-generation platinum compound used in the treatment of colorectal cancer, gastrointestinal cancers, and few other malignancies. It is mostly used in combination regimens with 5-fluorouracil /leucovori...

Therapeutic and prophylactic effect of Andrographis paniculata on aspirin-induced gastric ulcer

Background: Andrographis paniculata is extensively used in the Southeast Asia in treating different kinds of diseases. Aims and Objectives: The study aimed to determine the chemical constituents of A. paniculata extract...

Comparative analysis of choice reaction times with randomly variable foreperiods in normal individuals and schizophrenic patients

Background: Reaction time (RT) is an index of brain’s biological efficiency. RT can indicate sensorimotor variability with varying foreperiods (FPs) and can indicate mental dysfunction like schizophrenia. Aims and Object...

A comparative study of lipid profile, body mass index, and waist circumference among Type 2 diabetes mellitus patients with poor and good metabolic control and normal age-matched control group

Background: Prevalence of dyslipidemia is very common in Type 2 diabetes mellitus (DM), and lipid abnormalities are likely to play an important role in the development of the atherosclerotic vascular disease. Type 2 diab...

Assessment of knowledge, attitude, and practice of pharmacovigilance among private practitioners in Southern India: A questionnaire-based study

Background: Pharmacovigilance has constantly gained importance in last 15 years, relating to absolute amount of adverse drug reactions (ADRs) and to the fact that several hospital admissions are due to ADRs. The success...

Download PDF file
  • EP ID EP287942
  • DOI 10.5455/njppp.2017.7.0821607082016
  • Views 62
  • Downloads 0

How To Cite

Mamatha V, Nagesh HN, Parashivamurthy BM (2017). A prospective observational study of use of antibiotics at emergency department in tertiary care hospital. National Journal of Physiology, Pharmacy and Pharmacology, 7(1), 103-107. https://europub.co.uk/articles/-A-287942