Comparison of effect of intranasal midazolam and dexmedetomidine as premedication on haemodynamic stability among paediatric patients
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1
Abstract
Background: Fear of unpleasant and painful procedures, separation from parents and an unwillingness to breathe through an anaesthesia face mask may produce stormy anaesthetic induction in unpremedicated patients. Because of this premedication should be an integral part of paediatric anaesthetic practice. Objective: To Compare the Effect of Intranasal administration of Midazolam and Dexmedetomidine as Premedication On Haemodynamic Stability Among Pediatric Patients. Methodology: A Prospective Comparative study was carried out at Department of Anaesthesiology at Shri M.P. Shah Medical College, Jamnagar, Gujarat from December 2011to May 2012. A total of 60 Pediatric Patients of of both sex age group between 1- 5 year from the routine surgical list of our Hospital were included in the study. The children were divided into groups i.e. 30 in each based on the premedication received and by random allotted numbers. Results: The two groups were comparable with regards to demographic data. There was no significant statistical difference in age,weight,sex, duration of surgery and type of surgery between the two groups. The Blood Pressure, Pulse and Respirator rate was found to differ between group after 30 min of drug administration. Spo2 was found to constant in both the groups. Conclusion: Intranasal dexmedetomidine causes some degree of cardiovascular depression in pediatric patients when administered by intranasal midazolam; however, they do impart cardiovascular stability to patients undergoing the stress of surgery.
Authors and Affiliations
Shilpa S Naik, Shobana Gupta
Keywords
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- EP ID EP440574
- DOI 10.26611/10158111
- Views 158
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