Comparison of Effectiveness of Dexmedetomidine versus Propofol during a wake Fibre-optic Naso-tracheal Intubation
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 5
Abstract
Awake fibreoptic intubation (AFOI) is often the preferred method for airway management in patients with difficult intubation. The success of AFOI is highly dependent on use of various sedatives, in addition to adequate preparation of airway. Although various pharmacological agents like fentanyl, ramifentanyl, midazolam, ketamine, propofol have been used for conscious sedation during AFOI, most of them have respiratory depressant effect in higher doses. Hence there is a need for an ideal sedative agent for AFOI that will not cause respiratory depression, also minimize undue discomfort and anxiety. The purpose of this study was to compare the effectiveness of Dexmeditomidine with propofol for conscious sedation during awakefibreopticnasotracheal intubation. Methods: Eighty patients with ASA (American society of anaesthesiology) physical status I and II, with age group between 18 to 55 years, were randomly divided into Dexmeditomidine (D) and Propofol (P)group. Patients with Group D were given intravenous Dexmeditomidine (n=40) 1µg /kg infusion over 10 mins. Group P were given propofol (n=40) 70 µg /kg min over 10 mins. Airway prepared by topical anaesthetic and airway blocks. Effectiveness of Dexmeditomidine and Propofol for patient’s intubating conditions , patient’s tolerance as graded by a scoring system, and hemodynamic changes were evaluated . Results: AFOI was successful in all patients. The patient’s comfort score was better in dexmditomodine group. The dexmeditomidine group experienced fewer airway events and less heart rate response to intubation than the propofol group. Conclusion: Dexmeditomidine group allows better tolerance, more stable hemodynamic status and preserves a patent airway.
Authors and Affiliations
Sanyogita Naik
Keywords
Related Articles
- EP ID EP538438
- DOI 10.21088/ijaa.2349.8471.5518.27
- Views 96
- Downloads 0
Comparison of Laryngeal Mask Airway and Endotracheal Intubation in Paediatric Patients: A Comparative Study
Aim: The aim of the present study was to compare the subsequent factors that take place during laryngeal mask airway insertion and endotracheal intubation for surgical procedures under general anesthesia. The parameters...
Combined Psoas Compartment Block and Sciatic Nerve Block for Elective Lower Limb Surgeries
Introduction: Lower limb orthopedic interventions such as total hip arthroplasty (THA) and total knee arthroplasty (TKA) present a challenge to the anesthetist, as these procedures typically involve elderly patients ofte...
A Study on the Efficacy of Ketamine Given Intrathecallyas A Spinal Anesthetic Agent
Ketamine a phencyclidine derivative with potent analgesic properties possesses few advantages over the other local anesthetics as it tends to stimulate the cardiovascular system and maintains the respiratory response to...
Effect of Adding Potassium Chloride to Bupivacaine in Brachial Plexus Block: A Cross Sectional Case Control Study
Brachial plexus blockade for upper limb surgeries is the most common major peripheral nerve block technique and a significant difference exists between the onset times of various agents when these blocks are used. Adjuva...
Is Thoracic Epidural Anesthesia a Better Alternative to General Anesthesia in Modified Radical Mastectomy Surgeries?
Background and objectives: Though the breast surgeries are usually performed under general anesthesia (GA), it is not without any attendant risks. Thoracic Epidural anesthesia (TEA) is gaining more attention in view of b...