Comparison of Epidural Ropivacaine and Ropivacaine Clonidine Combination for Elective Caesarean Sections among Two Groups Ropivacaine and Ropivacine With Clonidine.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 1
Abstract
Background and Aim: The aim is to determine the qualitative and quantitative aspects of epidural block of ropivacaine 0.75 % ( 20ml) versus ropivacaine 0.75% with clonidine (30mcg) for elective cesarean section. Settings and Design: A randomized doubleblind study was conducted among 60 healthy parturients, scheduled for elective cesarean section, at JNMC, wardha, India. Materials and Methods: Epidural block was administeredwith 20 ml of ropivacaine 0.75% (group R) and ropivacaine 0.75% andclonidine 30 μg (group RC) and anesthetic level was achieved minimum untilT6T7 dermatome. Onset time of analgesia, sensory and motor block levels, maternal heart rate and blood pressure, neonatal Apgar scores, postoperativeanalgesic dose and adverse events were recorded. Results: 60 patientswere enrolled in this study and were subjected to statistical analysis. Groupswere comparable with regard to demographic data, neonatal Apgar scores and incidences of side effects except for the higher incidence of dry mouth inpatients of RC group. Onset of analgesia was much shorter in RC group along with prolonged duration of analgesia. The incidence of bradycardia andhypotension was more in RC group as compared to R group which wasstatistically significant. The dose requirement for postoperative pain reliefwas significantly lesser in RC group. Conclusions: The addition of 30 μgclonidine to isobaric epidural ropivacaine results in longer, complete andeffective analgesia with similar block properties and helped to reduce theeffective dose of ropivacaine when compared with plain ropivacaine for caesarean delivery.
Authors and Affiliations
Dr. Lalit Jadhav
Keywords
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