Comparison of Equipotent Doses of Cisatracurium and Rocuronium at Bhuj, Kutch
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 3
Abstract
Background and Aim: For several decades, suxamethonium was the gold standard relaxant for rapid sequence intubation. However, the unintended side-effects such as muscle fasciculation, hyperkalemia, rise in intracranial and intraocular pressures led to the search of newer relaxants. In this study we compared the most recent rocuronium and cisatracurium at a dose as regard the onset of action, intubating conditions, efficacy, and safety during general anesthesia for adult gynecological ambulatory surgery. Materials & Methods: Total of 90 patients were randomly selected and included in the present study. The age range for the patient was found to be 25 to 65 years. All the included patients were randomly divided into two groups, 45 patients in each group. In the first group Rocuronium 0.6 mg/kg was administered and in other group 0.1 mg/kg was administered. Results: The time to achieve maximum blockade was 160.4 sec and 85.94 sec respectively in Group A and Group B. The clinical duration was found to be 48.9 mins and 32.8 min respectively in group A and B. Total intubation score achieved at 60 secs was 6.36 and 8.12 seconds respectively for group A and group B. Conclusion: Rocuronium has a rapid onset of action with good intubating conditions, Cisatracurium has an intermediate duration of action, and both are potent and safe with excellent cardiovascular stability and without apparent histamine release.
Authors and Affiliations
Hemali Chande
Keywords
Related Articles
- EP ID EP472089
- DOI 10.21088/ijaa.2349.8471.4317.41
- Views 110
- Downloads 0
Efficacy of Right Superficial Cervical Plexus Block and Intravenous Dexmedetomidine for Relief of Shoulder Pain in Laparoscopic Surgery Under Spinal Anaesthesia: A Feasibility Study
Background and Aim: Laparoscopic procedures are conventionally done under general anaesthesia for avoiding patient discomforts and shoulder pain due to pneumoperitoneum that occur during laparoscopy under spinal anaesthe...
Supraclavicular Brachial Plexus Block: A Comparative Clinical Study between Bupivacaine and Levobupivacaine
The racemic bupivacaine is commonly used local anaesthetic drug brachial plexus block in as it provides longer duration of action but has risk of cardiotoxicity .The use of levobupivacaine in brachial plexus block seems...
Spinal Anaesthesia with Midline and Paramedian Technique in Pregnant Patients undergoing Lower Segment Caesarean Section Under Spinal Anaesthesia
Background and AIMS: Subarachnoid blockade is widely used due to its simplicity, low cost and reduced complications due to general anaesthesia. Subarachnoid space can be approached from midline or paramedian approach (PM...
Prospective Study of Dexmedetomidine-Propofol versus Dexmedetomidine-Ketamine for Sedation and Anesthesia in Hysteroscopic Examination and Procedures
Context: Dexmedetomidine a wonderful drug with vital organ protective properties. When combined with other intravenous anaesthetic agents useful in surgical procedure without intubation. Less research work was done on th...
A Comparison of Dexmedetomidine with Thiopentone Sodium Versus Esmolol with Thiopentone Sodium to Attenuate the Hemodynamic Stress Responses after Electroconvulsive Therapy
Modified electroconvulsive therapy (ECT) under anesthesia is an important in the treatment of severe, persistent depression; bipolar disorder and schizophrenia; especially resistant cases. However, it is commonly associa...