Comparison of Exfoliative Cytology of Tongue and Buccal Mucosa among Smokers and Non-smokers using PAP Stain and AgNOR Counts
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 7
Abstract
Introduction: Oral cancer can be detected at earliest stages by Oral cytology using PAP stain and AgNOR counts. Alterations in nuclei of oral superficial epithelial cells can serve as reliable indicators of dysplastic or neoplastic changes. A study was conducted to Compare the Exfoliative cytology of tongue among smokers and non-smokers using PAP stain and AgNOR counts. Material and Methods: Comparative study of evaluation of cellular alterations in the smoker’s and non smokers oral mucosal cells was performed. Exfoliative Citology technique were used and the cytologic smears stained with AgNORs and PAP stain. Cytologic smears were collected from two anatomic sites, buccal mucosa and lateral tongue border with the purpose of relating smoking with the quantitative analyses of the AgNORs. Result: It was found that the average number of AgNORs/ nucleus is related with smoking. These results suggest a possible relation between smoking and an increase rate of cellular proliferation in the oral mucosal cells. Conclusion: It is concluded that the proliferative activity is enhanced in smokers compared to non smokers and hence suggestive of adverse effects of smoking on oral and general health.
Authors and Affiliations
Owais Gowhar
Keywords
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