Fluid Resuscitation: Ringer Lactate Versus Normal Saline-A clinical Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 11
Abstract
Introductuion: Field of trauma care has evolved tremendously, generally blood products are recommended for fluid resuscitation however in situations where the blood products are not available there may be a need for replacement with suitable replacements fluids like Ringer Lactate and Normal saline. This study compares the efficacy of both the replacement fluids on hemodynamics and metabolic responses of the patients. Material and Methods: This study was conducted in Hospital 26 patients with mild haemorrhage after trauma was selected for the study. They were divided randomly into two groups Group I receiving Normal Saline and Group II receiving RL. Hemodynamics were measured and blood samples were collected at 0 minutes, 15 min, 1 hour, 3 hours and 6 hours after resuscitation and the data was recorded and analyzed. Results: The Normal Saline group resuscitation with 139 ± 10ml/Kg produced MAP values to the level of 83.75mmHg. In LR group resuscitation with 100 ± 10ml/Kg produced the Mean arterial pressure values of 85.42mmHg. Base excess was lowered by hemorrhage and resuscitation with Ringer lactate improved the Base Excess but not with Normal saline. Serum Potassium levels were found to be increased with Normal saline but not with Ringer Lactate. Conclusion: Ringer Lactate is found to be superior to Normal saline for fluid resuscitation because Normal saline has vasodilator effects with the increase in serum potassium levels and risk of metabolic acidosis. Although there were no significant differences found in the clinical outcomes, duration of admission and hospitalization between patients resuscitated with Normal Saline and Lactate Ringer solution.
Authors and Affiliations
Anil S. Mane
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