Comparison of Fine Needle Aspiration Cytology & Cell Block in Thyroid Pathology
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 2
Abstract
Context: Accurate preoperative diagnosis of thyroid lesions is imperative and helps surgeons to decide the management of the patients. The differential diagnosis of these nodules includes from non neoplastic to malignant lesions. Aims: This study was conducted to assess the utility of cell blocks in hemorrhagic and cystic thyroid aspirations. Settings and Design: This was a prospective study conducted over a period of one year in the department of Pathology. Methods and Material: All Thyroid FNAs that yielded either blood tinged colloid or cystic fluid or hemorrhagic material were included in the Study. CBs were prepared from the residual material after preparation of smears. The cytomorphology of FNA smears were compared with histopathology of cell blocks in all cases. Results: Sensitivity, specificity, PPV, NPV of FNAC was 100%, 94.2%, 83.3%, 100% respectively. Percentage of false positive cases was 5.7% with diagnostic accuracy of 95%. In the present study Cell blocks were contributory to FNAC diagnosis in three cases (6%). Conclusions: Cell block preparation as an adjuvant to FNAC can reduce diagnostic pitfall and improve accuracy of FNA diagnosis. It gives an added opportunity to study architecture of the tissue. Cyto-histologic correlation in all cases may help to improve efficiency of Pathologists.
Authors and Affiliations
Padmaja Kulkarni
Keywords
Related Articles
- EP ID EP462889
- DOI 10.21088/ijprp.2278.148X.6217.9
- Views 91
- Downloads 0
Bone Marrow Iron Stores among Various Hematological Disorders
Background: Nutritional anemia, particularly iron deficiency, continues to be a major public health problem worldwide, particularly in the developing countries like India. Although mass spectrometry has been recently use...
Distribution of ABO and Rhesus (D) Blood Groups among Blood Donors in Tertiary Care Rural Hospital of Central India: A Retrospective Study
Introduction: A lot of diversity is present in a vast country like India in relation to race, religion and creed. Similar to it the geographical distribution of ABO and Rhesus blood groups varies across the country. This...
Preoperative Levels of Serum Total Antioxidants and Sialic Acid in Leiomyoma: A Case Control Study
Background: The exact cause of leiomyoma which affects at least 5 million women throughout the world is not known. Currently there are only few markers for leiomyoma which includes serum protein, prolactin, CA 125, solub...
Cytological and Histomorphological Correlation of Salivary Gland Lesions: Study at a Rural Tertiary Healthcare Hospital
Aim/Objective: The objective of this study was to evaluate the diagnostic accuracy of FNAC in various salivary gland lesions and it’s correlation with histopathology, which helps in the appropriate management of the pati...
Reproducibility and Utility of Implementing the Bethesda System for Reporting Thyroid FNAC Smears
Introduction: Thyroid Fine Needle Aspiration (FNA) has been widely used as a firstline investigation to assess thyroid nodules, as it is rapid, cost effective, safe and reliable.To bring uniformity and standardization i...