COMPARISON OF INTRAVENOUS PARACETAMOL AND TRAMADOL AS PRE-EMPTIVE ANALGESIC FOR LOWER ABDOMINAL SURGERIES IN CHILDREN- A PROSPECTIVE RANDOMISED DOUBLE-BLIND STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 9
Abstract
BACKGROUND Pre-emptive analgesia is administration of an analgesic before a painful stimulus, so as to prevent central sensitisation. Intravenous (IV) formulation of paracetamol has been introduced and its safety and pharmacokinetic properties have been established for children providing excellent analgesia and avoiding side effects associated with opioids and non- steroidal antiinflammatory drugs. Present study was done to compare the analgesic effects of pre-emptive I.V. paracetamol and tramadol in children undergoing lower abdominal surgeries. MATERIALS AND METHODS Sixty-four children of ASA physical status I and II, aged 2 to 12 years scheduled for elective lower abdominal surgeries under general anaesthesia were recruited for a prospective, randomized controlled, double blinded study, into group P and group T. Following induction, group P received 15 mg/ kg I.V. paracetamol and group T 1 mg/kg tramadol in 75 ml of normal saline over 15 minutes before surgical stimulus. Postoperative modified objective pain scale (OPS), time to first rescue analgesia (FRA), Aldrete score, time to reach Aldrete score> 9, sedation scores, parent satisfaction scores and PONV were recorded for 24 hours. RESULTS Mean pain scores by OPS in group P and T were similar and statistically insignificant. Time to FRA being 320 ± 20 min in group P as compared to group T 340 ± 30 min. 12.5% patients had PONV in group P as compared to 81.5% in group T (p≤0.05). Mean duration to reach Aldrete score of 9 was 11 ± 1.5 min and 16.7 ± 3 min in group P and T respectively (p≤0.05). CONCLUSION Pre-emptive I.V. paracetamol is as efficacious as I.V. tramadol for postoperative analgesia with early recovery and lower incidence of PONV in paracetamol group.
Authors and Affiliations
Seham Syeda, Jyothi B, Pratishruti Singh, Safiya I. Shaikh
Keywords
Related Articles
- EP ID EP555113
- DOI 10.14260/jemds/2019/133
- Views 102
- Downloads 0
CLINICO-MICROBIOLOGICAL ASPECT OF MALARIA IN A TERTIARY CARE HOSPITAL
BACKGROUND Malaria is a major cause of mortality and morbidity in the tropical and subtropical regions of the world. The incidence of malaria worldwide is estimated to be 300 - 500 million. India accounts for 77 percent...
PREVALENCE OF THYROID DYSFUNCTION AMONG ANTENATAL WOMEN IN A TEACHING HOSPITAL
BACKGROUND Thyroid disorders in pregnancy can affect the health of the mother and child, before and after delivery leading to adverse maternal and foetal outcome. The aim of the study is to study the prevalence of thyroi...
A CLINICAL STUDY ABOUT INCIDENCE OF OCCULT MALIGNANCY IN LONGSTANDING MULTINODULAR GOITRE
BACKGROUND Goitre is one of the common features of thyroid disease presentation. Most of the thyroid nodules were found accidentally by Ultrasound and clinical evaluation. Historically chances of malignancy in Multinodul...
I-GEL AS AN AIRWAY DEVICE- A PROSPECTIVE STUDY IN 30 PLASTIC SURGICAL PATIENTS
BACKGROUND Supraglottic airway devices have become invaluable for both routine and difficult airway management. After the introduction of the laryngeal mask airway LMA-Classic in the 1980s, there has been a steady increa...
PATTERN OF SURGICAL TRAUMA- A RETROSPECTIVE STUDY
BACKGROUND Surgical trauma is known to be an important public health problem throughout the world and so also in metropolitan cities in our country, due to erratic traffic and poor response by onlookers as well as poorly...