Comparison of isobaric levobupivacaine versus hyperbaric bupivacaine in spinal anesthesia for cesarean section: A prospective randomized case control study
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 4
Abstract
Introduction Isobaric levobupivacaine is now being investigated in spinal anesthesia owing to its better safety profile however the studies are sparse which show clinical efficacy of intrathecal isobaric levobupivacaine alone in its ED95 dose 125135mg for cesarean sections CS and its comparison with most commonly used regime of hyperbaric bupivacaine 10mgObjective and Methods 100 parturients undergoing CS in spinal anesthesia were randomized in two equal groups to receive either 125mg isobaric levobupivacaine group L or 10mg hyperbaric bupivacaine group B Sensory motor block characteristics onset extent and duration hemodynamic profile adverse effects and success rate of the two drugs were comparedResults All patients in both groups achieved target sensory level of T6 and Bromage score of 3 complete motor block hence no patient required anesthetic supplementation resulting in 100 success rate in both groups Sensory onset Time to T6 was significantly faster in group B 38081 min than in Group L 428104 min p 0011 Motor onset Time to B3 was also significantly faster in Group B 304069 than in group L 356063 p 00002 However this difference of 1 xssremovedConclusion Isobaric levobupivacaine 125mg can be used as an alternative to hyperbaric bupivacaine 10mg in spinal anesthesia for cesarean section as it offers effective sensory motor blockade with clinically comparable onset timeKeywords Isobaric levobupivacaine Hyperbaric bupivacaine Spinal anesthesia Caesarean section
Authors and Affiliations
Udita Naithani, Madhanmohan C, Megha Gupta, Virendra Verma, Pankaj Damor
Keywords
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- EP ID EP476510
- DOI 10.18231/2394-4994.2018.0104
- Views 98
- Downloads 0
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