Comparison of Lignocaine, Diltiazem and Combination for Controlling the Cardiovascular Responses to Tracheal Intubation-A Cohort Study
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 9
Abstract
Endotracheal intubation has turned out to be a routine procedure in the modern-day anesthesia care by the middle of the last century. However, this procedure results in transient cardiovascular changes, which could result in potential complication in physiologically deranged population. We conducted this study to compare the effects of two drugs, namely lignocaine and diltiazem alone and in combination in attenuating the deleterious effect of intubation on cardiovascular system. The setting of this prospective comparative study was government medical college Thiruvananthapuram. We studied 45 cases of ASA Gr. I & II between age groups 20-65 years, involving both sexes coming for major elective surgical procedures. Each group consisted of 15 patients. Heart rate, systolic and diastolic blood pressures were monitored at different time points. We analyzed the data with stata IC 15 software. The outcome measures were compared with repeated measures ANOVA. The median age with inter quarter range of the patients was 36(28-45) years. There were more females in the study groups (80percent). Systolic and diastolic pressure varied at different time points in the groups studied, within the groups and across the groups. Systolic and mean arterial pressure showed initial rise and later a downward trend across the group. There was a statistically significant difference between the three groups studied (p<0.05). The study revealed that SBP, DBP and MAP increased briefly after tracheal intubation in all patients who had received lignocaine, diltiazem or diltiazem plus lignocaine before intubation.
Authors and Affiliations
Dr Sugandha 1
Keywords
Related Articles
- EP ID EP526168
- DOI -
- Views 72
- Downloads 0
Vitamin D Insufficiency in Women Inadequately Exposed to Sunlight: A Comparative Observational Study
Introduction: Vitamin D is a catabolic product of cholesterol metabolism. Conversion of 7-dehydrocholesterol to active vitamin D is largely dependent upon exposure to Ultraviolet B rays coming from sunlight. The individu...
A Study of Efficacy of Alvarado Score vs Ultrasonography in Evaluation of Suspected Appendicitis
Background: Acute appendicitis is the most common cause of an ‘acute abdomen’ in young adults. Notwithstanding advances in modern radiographic imaging and diagnostic laboratory investigations, the diagnosis of appendicit...
Lesions of the Foreskin – Histopathological Study of Circumcision Specimens
Foreskin or prepuce is the anatomical covering of male external genitalia. It covers the distal part of external surface of penis. Diseases of foreskin may manifest as an array of pathological conditions which includes n...
Outcome of Non Invasive Ventilation in Children with Acute Respiratory Failure
Introduction: During the last 10 years NIV has been increasingly used in children with acute respiratory distress and failure. Recently some prospective studies have shown that NIV appears to be a safe and effective trea...
Use of computer assisted teaching learning methods and internet among the teachers in a Medical College
Background: The aim of present study is to know the extent of the use of computer based teaching learning methods and internet among the teachers in Medical Education. Materials and Methods: A questionnaire based study w...