Vitamin D Insufficiency in Women Inadequately Exposed to Sunlight: A Comparative Observational Study
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
Introduction: Vitamin D is a catabolic product of cholesterol metabolism. Conversion of 7-dehydrocholesterol to active vitamin D is largely dependent upon exposure to Ultraviolet B rays coming from sunlight. The individuals not exposed to adequate sunlight are prone for developing vitamin D deficiency conquest upon inadequate conversion of 7-dehydrocholesterol to provitamin D3 and Active Vitamin D. Vitamin D deficiency is one of the common problems in south East Asian women in child bearing age groups. This is not only detrimental for the women but also may cause intrauterine growth retardation, low birth weight and adverse pregnancy outcome. The common causes of vitamin D deficiency include increasing age, inadequate exposure to sunlight and chronic diseases. In south East Asian countries many females are not adequately exposed to sunlight moreover their nutrition also is deficient in vitamin D. We have conducted this study to know the vitamin D status of females not adequately exposed to sunlight due to reasons like housewives constantly remaining in home, dressing style, young girls using excessive sun screen and those belonging to high socioeconomic status who usually remain in air-conditioned environment mostly restricted to homes, offices or cars. Aims and Objectives: To determine the frequency of vitamin D deficiency or insufficiency in women residing in twin Cities of Hyderabad and Secunderabad who are not adequately exposed to sunlight. Materials and Methods: This was a case control study carried out in a tertiary care hospital situated in Hyderabad. 36 Women with no co-morbidities and having history of inadequate exposure to sunlight were enrolled in this study as cases. Control group comprised of women of similar age and physical characteristic who were determined, on the basis of detailed history, to have adequate exposure to sunlight. In both these groups detailed histories was taken with a view to exclude co-morbidities and know the status of sun exposure. Investigations like CBC, Sr Calcium and ALP were done in all the cases. The data was tabulated and analyzed using SPSS 16.0 version software. Results: The mean weight and BMI were comparable in cases and controls. The mean weight of control group was 59.38 +/- 2.72 kg while in cases group the mean weight was 64.38 +/- 3.52 kg. While mean height in control and cases group was 5.35 +/- 0.047 and 5.178 +/- 0.035 feet respectively. Serum calcium in cases and control groups was 8.869 +/- 0.126 and 8.635 +/- 0.121 while ALP was 98.30 +/- 7.97 and 104.04 +/- 4.770 respectively. Finally 25 (OH) Vit D was found to be 96.27 +/- 8.96 in control group and 73.403 +/- 4.42 in www.jmscr.igmpublication.org Impact Factor 5.84 Index Copernicus Value: 71.58 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v5i12.124 Dr Fahad Aleem et al JMSCR Volume 05 Issue 12 December 2017 Page 32035 JMSCR Vol||05||Issue||12||Page 32034-32040||December 2017 cases group. The findings confirmed the presence of via D insufficiency in cases group i.e. women not exposed adequately to sunlight. Conclusion: Vitamin D insufficiency and deficiency is a common occurrence in south East Asian women of child bearing age group. This is not only detrimental for women but also may cause an adverse pregnancy outcome. We recommend that all women should adequately be exposed to sunlight and should intentionally expose themselves to sunlight and take food rich in calcium (Fish, egg yolk, non-veg food and milk.). Vitamin D supplementation in appropriate doses should be given to women with vitamin D insufficiency or deficiency.
Authors and Affiliations
Dr. Fahad Aleem
Keywords
Related Articles
- EP ID EP521374
- DOI -
- Views 76
- Downloads 0
Glandular Odontogenic Cyst Rarely Seen in Maxilla- A Case Report and Review of Literature
Glandular odontogenic cyst is rare developmental odontogenic cyst of jaws, that ranges from 0.012 to 1.3%. Generally, this cyst is seen in the anterior areas of the mandible and with the mean age being 49 years. GOC is o...
An analysis of management of solid pseudopapillary neoplasms of Pancreas in a tertiary centre: 10 years experience
Background & Aim: Solid pseudo papillary neoplasm (SPN) is a rare tumor of the pancreas. The present study was aimed to evaluate the clinical and pathologic characteristics and surgical outcomes of SPNs. Methods: The cli...
Hepaticojejunostomy & Hepaticoduodenostomy in Biliary Reconstruction Following Excision of Choledochal Cyst – Which Is Better?
Choledochal cysts are rare congenital dilations of the biliary tree that can present with non-specific symptoms such as abdominal pain, jaundice, cholelithiasis and pancreatitis. Although most commonly identified in chil...
Brucellosis: Presentation, Diagnosis and Treatment: Case Report
Introduction: Brucellosis is one of the commonest zoonotic infections worldwide. the disease is endemic in Saudi Arabia, the Middle East, and the Mediterranean area, and whether in an endemic region or not, it remains a...
Study of Outcome of Subsequent Pregnancy following previous Caesarean Section in Katihar Medical College & Hospital, Katihar
Objectives: Our study was to evaluate the mode of delivery, operative difficulties of post caesarean section pregnancy, Frequency of postpartum complication, foetal and maternal morbidity and mortality in post caesarean...