Comparison of Peripheral Smear Finding with Bone Marrow Finding in HIV Patients
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Hematological abnormalities are a common complication of HIV infection. Present work was carried out to compare bone marrow abnormalities with peripheral hematological abnormalities in patients with HIV/AIDS. 160 patients of HIV +ve were included in the study. A complete blood count, relevant biochemical investigations, CD4 counts were done, besides a thorough history and clinical examination. HIV positive patients were classified as those having AIDS and those without AIDS according to NACO criteria. Bone marrow examination was performed for indication of anemia, leucopenia, pancytopenia and thrombocytopenia. As per CDC criteria 59.81% patients had AIDS in 107 patients. The most common hematological abnormality was anemia, seen in 93.12% patients. Bone marrow was normocellular in 79.06% of non-AIDS and 79.68% of AIDS, hypocellular in 13.95% of non-AIDS and 12.5% of AIDS, hypercellular in 06.97% of non-AIDS and 07.81 % of AIDS patients. For myelodysplasia in bone marrow in HIV patients we noted granulocytic dysplasia in 4.65% in Non –AIDS and 14.06% AIDS patients. Erythrocytic dysplasia in 9.30% in Non –AIDS, 12.5% in AIDS group. Thrombocytopenia was seen in4 cases of ART (4.93%) and 3 cases (4.68%) of AIDS group. Abnormal cells like plasma cell, histocyte and toxic granule were also found. In conclusion, Myelodysplasia was more common in AIDS than in non AIDS patients. Granulocytic series is most commonly associated with evidence of dysplasia. Anemia in HIV patients can be a good clinical indicator to predict and access the underlying immune status. Thus present study is imperative to methodically observe and follow clinical and laboratory aberration in such patients in order to improve our diagnostic and therapeutic skills pertinent to HIV/AIDS.
Authors and Affiliations
Dhurve Sharad A, Dhurve Alka S
Keywords
Related Articles
- EP ID EP374588
- DOI -
- Views 74
- Downloads 0
Knowledge and Preventive Practices Regarding Dengue among Dengue Fever Cases Admitted at Tertiary Care Hospital, Rajkot, Gujarat, 2014
Abstract: Dengue is the most common disease among all the arthropod-borne viral diseases. Due to remarkable changes in the epidemiology of dengue, currently dengue ranks the most important mosquito-borne viral disease in...
Study on Effect of PGE2 Gel for Induction of Labour
Abstract: The aim of this study to the effect of intra cervical PGE2 gel for induction of labour. 177AN patients induced with PGE2 gel over a period of one month, July 2017 at Government Rajaji Hospital, Madurai were stu...
Correlation between Thyroid Stimulating Hormone and Cholesterol and Triglyceride level in Udaipur Population
A series of studies reported that a high level of TSH was associated with a deleterious change of serum lipids, with an increase of lipid abnormalities. The present study evaluated the relationship between TSH and choles...
The Bioactive Compounds Obtained from the Fruit-Seeds of Madhuca longifolia (L) Act as Potential Anticancer Agents
Abstract: Madhuca longifolia (Mahua)is a mediumto large sized deciduous tree belonging of amily Sapotaceae, commonly known as the Butter nut tree. Madhuca longifoliais reported to contain sapogenins, triterpenoids, sapon...
We Are Now Standing On Not Normal Land: Nurses' Competency in Disaster Management
Abstract: Currently, the incidence of disasters is the biggest catastrophes that threaten people’s livelihoods, health, and others welfare around the world. This situation provides the challenges for health care professi...