Comparison of Placental Histopathology in IUG Rand Normal Term Infants: A Cross-Sectional Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Introduction: Healthy development of fetus is dependent on normal placental development. Alteration in the placental development is the main etiopathological factor for IUGR. The present study aims to compare the histopathological findings of placenta in IUGR and normal term delivery. Materials and Methods: This cross sectional study was done at an Army zonal Hospital from Jan 2016 to Jan 2017. Sixty placenta were studied of which 30 belonged to the IUGR group and other 30 were from normal term fetus( Control group). Inclusion criteria was maternal age between 20 to 35 yrs, Gestational age between 32 to 40.5 wks with IUGR(USG confirmed) or normal healthy fetus. Exclusion criteria were twin pregnancy, gestational age <32wks, and diabetes. Data of mother, newborn and placenta were recorded after delivery. The subjects were matched for age, height, weight, social status. Data were analyzed using SPSS software version 16. Results: Infarction rate, thrombosis, tissue ischemia, intervillous haemorrhage and intervillous fibrin deposition were significantly higher in IUGR group. Mean placenta weight was lower in IUGR group (380 gms vs. 510 gms). Conclusion:Placenta of IUGR newbornswere smaller with more microscopic infarction. The findings suggest that chronic ischemia and associated secondary changes probably lead to improper perfusion and IUGR. The gross and microscopic measurements of a placenta are more objective and seem to offer a good way to get proper information about IUGR. Therefore a detailed history of placental study should be taken during ANC visit of a lady with previous history of IUGR and manage the case accordingly.All IUGR fetuses must be considered at risk for poor placental circulation and hypoxia along with compromised nutrition. This study therefore indicates that study of fetal blood supply must be done as a part of surveillance of IUGR cases by Doppler study and other tests of fetal well-being must be carried out during antenatal period frequently and they must be delivered as soon as the fetal maturity is reasonably assured or there are any signs of fetal compromise.
Authors and Affiliations
Suneeta Singh, Arpitha Pemmarajub, Devendra Nema
Keywords
Related Articles
- EP ID EP590841
- DOI 10.9790/0853-1601103640.
- Views 67
- Downloads 0
Partogram: A Simple and Effective Tool In Monitoring the Progress of Labour
Objective: To determine the utility of partogram in monitoring the progress of labour and determining whether appropriate interventioms based on it will improve the fetomaternal outcomes. Method: A case controlled, prosp...
Intralesional Vitamine-D3 in Multiple Skin Warts
Background- Skin warts is a fairly common condition and primarily treated with destructive method which may be associated with scarring in multiple warts. Treatment with intralesional injections has gained momentum due t...
Abdominal Tuberculosis – A Clinical Perplexity In Diagnosing Acute Abdomen: Case series
Abdominal tuberculosis accounts for about 10% among the acute abdomen cases. The diagnosis of acute abdomen cases is confusing, especially when there is no history of primary pulmonary tuberculosis. It is a diagnostic ch...
Osseointegration- Key Factors Affecting Its Success-An Overview
During the past two decades, dental implants have been used extensively to achieve osseointergration for prosthetic rehabilitation of edentulism. For this, a surgical procedure is performed on patient to insert a foreign...
Management of Isolated Zygomatic Arch Fractures; Keens Buccal Sulcus Approach. A Case Report
The incidence of isolated Zygomatic arch fractures in a maxillofacial trauma is most common or second after nasal fractures. Various authors have presented different methods for its effective management.. We present a ca...