Intralesional Vitamine-D3 in Multiple Skin Warts
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Background- Skin warts is a fairly common condition and primarily treated with destructive method which may be associated with scarring in multiple warts. Treatment with intralesional injections has gained momentum due to its efficacy in clearing not only the local warts but also distant warts by stimulating the cell-mediated immunity against human papillomavirus. Aims- To evaluvate the safety and effectivness of intralesional Vitamin D3 for the treatment of multiple skin warts. Materials and Methods- Patients with multiple ( ˃2 in number ) skin warts were selected for immunotherapy. Intralesional Vitamin D3 (0.2 ml, 15 mg/ml) was given at the base of each wart after injecting with lignocaine (0.2 ml, 20mg/ml).The injections were repeated at 2 weeks interval for a maximum of 4 sessions or until complete resolution, whichever was earlier. A maximum of 2 warts per session were treated and patients were followed up for 6 months after the last injection. Results- Total 36 patients with multiple skin warts were included for the study .Among 36 patients, 18 had palmoplantar warts, 14 had verruca vulgaris, 3 had periungual wart and 1 patient had filiform wart. Out of 36 patients 25 (69.44 %) had complete resolution of their warts, both at the injection and distant sites, 8 ( 22.22 % ) had very good response and 3 ( 8.33 % ) had good response. No any serious side effect were reported. Conclusion- Intralesional vitamine-D3 injection is a safe, well-tolerable, inexpensive and effective treatment for multiple skin warts.
Authors and Affiliations
Arvind verma, Subhash Bishnoi, Manmohan Bagri, Savita Agarwal
Keywords
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- EP ID EP557581
- DOI 10.9790/0853-1803137478.
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