Comparison of Rectal Misoprostolwith IM Oxytocin in Prevention of PPH in Tertiary Care Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background: PPH, the leading cause of maternal death worldwide is almost entirely a preventable condition. The majority of these deaths occur within 4 hours of delivery, which indicates that they are a consequence of the third stage of labour. Aims and Objectives: To compare the effect of Rectal Misoprostol and IM Oxytocin in prevention of post partum haemorrhage. Patients and Methods: An open labelled, prospective, randomisedobservational study was carried out in GMH, Hyderabad. 200 pregnant women in active labour, fulfilling the inclusion criteria were enrolled for the study. As a part of active management of third stage of labour , 10 IU of IM oxytocin and 600μg of rectal misoprostol were given to control and study groups of 100 each respectively.Paired t test to compare within the group and unpaired t test for intergroup analysis was used, with level of significance 0.05. Results:Rectal misoprostol 600μg is as effective as 10 IU intramuscular oxytocin in minimizing blood loss in the third stage of labour. Conclusion: Misoprostol can be recommended for routine use as uterotonic in prevention of post partum haemorrhage in low resource settings, where storage conditions for oxytocin are not met and in the absence of skilled birth attendant.
Authors and Affiliations
Dr. Praveena Gungam, Dr. Pruthvi Desireddy, Dr. Preethi Kola, Dr. Swathi Rapole, Dr. V. Naga Jyothi, Dr. Kasu Akshara
Keywords
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