Comparison Of Stress Response During Direct Laryngoscopic Versus Fibreoptic Orotracheal Intubation Following Premedication With Dexmedetomidine.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Introduction Laryngoscopy and intubation is known to cause a significant stress response elicited as sympathetic overactivity. This may be seen as an elevation in heart rate, blood pressure, and catecholamine levels in blood. This can be deleterious in patients with poor cardiac reserve and other comorbidities. Dexmedetomidine is a novel α2 adrenergic agonist which has been shown to attenuate the pressor response following direct laryngoscopic intubation. A comparison of the attenuation of stress response during direct laryngoscopic and fibreoptic intubation following premedication with dexmedetomidine has been studied. Method 60 patients, with ASA grade I and II, of both sexes, aged 18 to 60 years, undergoing elective surgery under general anaesthesia, with endotracheal intubation were enrolled in this study & randomized into two groups; Group I intubated with fibreoptic bronchoscope and Group II intubated with direct laryngoscopy. Both groups were premedicated with dexmedetomidine 30 minutes before the surgery. Results The systolic blood pressure, diastolic blood pressure, mean arterial pressure and heart rate were all significantly lower in the fibreoptic intubation group. Although the time taken for intubation was significantly longer, the stress response were better controlled in the fibreoptic intubation because of less airway manipulation and noxious stimulation. Conclusion Dexmedetomidine attenuates the stress response significantly better in patients intubated with fibreoptic bronchoscope compared to patients intubated by direct laryngoscopy.
Authors and Affiliations
Sulochana Darjee
Keywords
Related Articles
- EP ID EP554996
- DOI 10.9790/0853-1803067885.
- Views 48
- Downloads 0
Changing Trends in Clinical Profile and Management of Liver Abscess? : Prospective Study in a Tertiary Care Hospital.
Background: Though Pyogenic liver abscess is a life threatening disease, there has been significant change in the epidemiology management and mortality over the years. Aim of the study was to review the literature and as...
Relationship between Iron Storage, Anti Oxidant Status and Number of Transfusion In Beta-Thalassemia Patients: A CrossSectional Study
Blood transfusionis the most common therapeutic aspect as well as life-saving measure for βthalassaemic major patients but repeated transfusion is related to iron overload and storage in the body and if untreated it may...
A Clinicopathological Study of Necrotizing Pancreatitis with Special Emphasis on Need for Surgery and Its Outcome
Necrotizing pancreatitis is one of the important causes of mortality in acute pancreatitis especially when it is infected. Intervention is very rarely indicated in patients with sterile necrosis but may be required in th...
Role of HsCRP in Predicting the Severity in Acute Ischemic Stroke Patients Attending the Tertiary Care Centre in Puducherry.
Background: Ischemic stroke is one of the major cause of disability worldwide. High sensitive Creactive protein plays a major role in acute stroke as a marker of inflammation. Aims: 1) To evaluate high sensitive C reacti...
Result of Type-I Tympanoplasty in Patients of Geriatric Age Group With Mucosal Type ofchronic otitis Media In A Rural Based Tertiary Care Hospital:
Objective: The aim of this study is to evaluate the result of type-Itympanoplasy in geriatric age group (age > 60 years) in terms of closure of perforation and hearing improvement. Study Design: It’s a prospective study...