Comparison of Suxamethonium with Rocuronium for Endotracheal Intubation
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2014, Vol 9, Issue 1
Abstract
Background: In the present day practice, muscle relaxation is used for facilitation of endotracheal intubation and to provide muscle relaxation throughout the surgery. Rocuronium bromide is a nondepolarizing aminosteroidal, vecuronium derivative drug with intermediate duration Side effects of suxamethonium are not observed with rocuronium bromide. Present study is aimed at determining the efficacy of rocuronium for routine endotracheal intubation within 60 seconds in general population. Objective: To compare the intubating conditions of rocuronium bromide with suxamethonium chloride. Methods: Patients were premedicated with inj. midazolam 0.05mg kg-1, inj. Pentazocine 0.5mg kg-1 and inj. glycopyrolate 0.005 mg kg-1, after which patients were preoxygenated for 03min with 100% oxygen. Induction was done with inj.thiopentone at the dose of 5mg kg-1. After loss of eye lash reflexes, muscle relaxant (rocuronium bromide/ suxamethonium chloride) was given as iv bolus. Intubating conditions were assesed at 60 seconds after injection of muscle relaxant, if intubating conditions were unsatisfactory, then repeat scopy was attempted after every 30sec interval (90, 120, 150 and 180 sec). Bag mask ventilation with 100% oxygen was continued till the repeat scopy was attempted. Monitoring of pulse rate, oxygen saturation, systolic and diastolic blood pressures, electrocardiogram were recorded immediately after laryngoscopy, at 5 and 10min after intubation. Results: Suxamethonium showed acceptable intubating conditions in 100% of cases at 60 Sec. out of which 93.24% were excellent. In rocuronium Group 100% of cases had acceptable intubating conditions at 60 sec. out of which 77.7% excellent and 22.2% good intubating conditions were observed. Conclusion: Rocuronium bromide at 0.9 mg kg-1 is a safe and good alternative for suxamethonium 1.5mg kg-1 for endotracheal intubation at 60 seconds. We advice rocuronium bromide 0.9 mg kg can be used for Rapid Sequence induction and Intubation, if there is no prediction of difficult intubation.
Authors and Affiliations
Pramod Bhale , Narender Bhandari , Selva Kumaran P , Rashmee Joshi
Keywords
Related Articles
- EP ID EP157645
- DOI -
- Views 112
- Downloads 0
Study of Serum Prostate Specific Antigen (PSA) Levels in Patients of Benign Enlargement of Prostate and Prostatic Cancer
Prostate specific antigen (PSA), neutral serine protease secreted exclusively by prostatic epithelial cells, has a number of applications in the management of men with prostatic carcinoma. While it is widely recognized t...
Comparative Study of Blood Glucose and Glycosylated Hemoglobin Levels and Clinical Profile in Low Body Weight (lean), Nonobese and Obese Type 2 Diabetes Mellitus
Background: Diabetes has emerged as a major public health problem in our country Insulin has important effects on key steps in metabolism of lipids and lipoproteins and altered lipid metabolism is common in diabetic pop...
High Dependency Units in Obstetric Care- Its Impact on the Maternal and Perinatal Outcome
This is a prospective descriptional study to evaluate the use of high dependency units in high risk pregnancy management and to assess the perinatal outcome and maternal mortality and morbidity among women admitted to HD...
Tropical Pulmonary Eosinophilia – A Rare Presentation of a Common Disease in Tropics
Tropical pulmonary eosinophilia is one of the many pulmonary infiltrates with eosinophilia. We are presenting a case with features of lung abscess in left lung field. The diagnosis was suspected and proved retrospe...
16S rDNA based identification of culturable bacteria from highly polluted Bangalore, India
This study investigated the microbial population of highly polluted Varthur and Bellandur lakes, the largest freshwater lakes of Bangalore, Karnataka. A motivation for this study was the umerous reports about these pollu...