Comparison of the effects of antiglaucomatous fixed combinations and patients compliance: dorzolamide-timolol maleate and latanoprost-timolol maleate
Journal Title: Dicle Tıp Dergisi - Year 2012, Vol 39, Issue 1
Abstract
Objectives: We aimed to compare the effects of fixed combinations of dorzolamide/timolol maleate (DTFC) and latanoprost/timolol maleate (LTFC) at primary open angle glaucoma patients and assess the patient compliance to treatment. Materials and Methods: Forty-four eyes of 24 patients taking LTFC, 35 eyes of 24 patients taking DTFC and totally 79 eyes of 48 patients were included in this study. Patients were followed for 6 months. At 3rd month, diurnal intraocular pressure (IOP) fluctuations were assessed. Perimetry and retinal nerve fiber layer (RNFL) analyze were repeated at 6th month. Results: Both medicines had efficiently controlled the IOP and diurnal fluctuations and statistically no significant difference was observed (p>0.05). Perimetric and RNFL measurements were not different in both groups(p>0.05). When we have compared the results of baseline and 6th months, MD and sLV values decreased, RNFL in some cases increased on the other hand we have also observed a decrease in some cases(p<0.05). Ocular irritation was the most common side effect in both groups and there was no statistically significant difference between the groups by means of side effects.When compliance and adherence were assessed, there was no statistically significant difference between the groups (p>0.05). Most of the patients did not forget to take their medicines (DTSK %54.2 and LTSK %66.7) and in following visits, compliance and adherence were improved in both groups. It is detected that duration of medicine use may affect the compliance (p=0.007). Conclusion: It is observed that two medicines controlled the IOP and diurnal fluctuations clinically efficient and effectively, had reasonable side effects and had high patient compliance to treatment.
Authors and Affiliations
İrfan Uzun, Kubilay Çetinkaya
Keywords
Related Articles
- EP ID EP129963
- DOI -
- Views 134
- Downloads 0
Subakut sklerozan panensefalitli hastaların ekokardiyografik değerlendirilmesi
Amaç: Subakut sklerozan panensefalit (SSPE), santral sinir sisteminin yavaş virüs enfeksiyonu sonucu ortaya çıkan kronik, progressif dejeneratif bir hastalığıdır. Bu hasta grubunun kalp fonksiyonları ile ilgili çalışm...
Üriner sistem infeksiyonlarından izole edilen Escherichia coli suşlarına fosfomisin trometamolün ve bazı antibiyotiklerin in-vitro etkinliği
Son yıllarda ülkemizde ve dünyada üropatojen E.coli suşlarında üriner sistem infeksiyonu tedavisinde sık kullanılan antibiyotiklere karşı duyarlılıkta azalma görülmektedir. Direnç nedeniyle tedavi yetersizliği ve ampirik...
The results of conjunctivolimbal autograft transplantation in primary pterygium
Objective: To evaluate the results of conjunctivolimbal autograft transplantation in the treatment of primary pterygium. Methods: One hundred and forty-eight eyes of 140 patients with primary pterygium were incl...
Clinical and demographic characteristics of children with congenital anomaly of kidney and urinary tract
Objective: Congenital anomaly of kidney and urinary tract (CAKUT) includes functional and structural anomalies that can cause end-stage renal disease in children. Clinical and demographic characteristics of patients wit...
Acil servise intihar girişimi ile başvuran yaşlı hastalarda mortaliteyi etkileyen sosyodemografik ve klinik faktörler
Giriş: Tüm dünyada olduğu gibi Türkiye’de de yaşlı nüfus oranı hızla artmaktadır. Buna paralel olarak ileri yaşta görülen psikiyatrik hastalıklar ve intihar eğilimi önem kazanmaktadır. Bu çalışmada, ilaç alımı ile intih...