Comparitive Study of Post Operative Endothelial Cell Loss in Diabetic versus Non Diabetic Eyes after Small Incision Cataract Surgery versus Phacoemulsification with IOL Implantation
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Abstract: The Aim of our study was to evaluate functional impairment in the corneal endothelium of eyes in patients with diabetes mellitus, after small-incision cataract surgery & after phacoemulsification as compared to non-diabetic patients in Indian population. We also compared endothelial cell morphology in diabetic and non-diabetic patients as a part of pre-operative evaluation of cataract patients undergoing cataract surgery either by SICS or phacoemulsification with IOL implantation as well as we compared postoperative endothelial cell loss between small incision and phacoemulsification cataract surgery. This study included 100 patients attending OPD from Jan 2013 to Dec 2013. Specular microscopy was done preoperatively and follow up done at 1 day, 5 days, and 1 month post operatively for the same parameters. Corneal edema was almost completely resolved in non diabetic patients while diabetic patients still showed increased CCT at 1 month. Rate of resolution was faster in non diabetic. Although Mean endothelial cell loss was statistically significant in diabetic patients but there was no significant difference in ECD loss when the 2 operative procedures were compared. (P value = 0.88). There was no significant difference in cell size variation between diabetics and non diabetics in both the procedures postoperatively. We concluded that cataract surgery is a big trauma for cornea, especially for its endothelium. The operation is mainly dangerous for patients suffering from diabetes. However, despite significant higher loss of endothelial cells and a significant slower process of cell repair in diabetic subjects, functional ocular status seemed unchanged.
Authors and Affiliations
Dr. Phoolchand Dhaka, Dr. Varsha Varshney
Keywords
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