Conjunctival Autograft using Autologous Serum versus Suturing Technique in Primary Pterygium: A Randomised, Prospective, Comparative Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Objective: To compare the efficacy of autologous serum and sutures in securing conjunctival autograftin the treatment of primary pterygium. Type of study: Randomised, Prospective, Comparative study. Materials and Methods: 60 eyes of 60 patients with primary advance pterygium attending our OPD in last 2 years were included in the study. All patients were categorised randomly using an online random number generator into 2 groups – group A and B (30 patients in each group). Pterygium excision followed by conjunctival autograft was done in all patients. In group ‘A’ graft was secured by 10-0 nylon suture and in group ‘B’ graft was secured by autologous serum. Surgical time, post-op discomfort and complications were compared in both the groups. Statistical Analysis: Data was collected using Microsoft Excel. P value <0.05 was taken as significant. Result: The mean operative time in group A was 33.73min (33.732.69) and in group B was23.83 min (23.831.91). Early Post operative discomfort was moderate to severe in 73.3% cases in group A, which was much more than in group B ( 20%).Graft retraction was found in 16.6%cases in group A and 30% in group B. In group A 46.6% and in group B 26.6% had graft oedema. One patient developed pyogenic granuloma and one had conjunctival cyst. Both patients belonged to group A. 2 patients (6.6%) of group B had graft loss on 1st post operative day. At 1 month visit the overall patient satisfaction was much higher in group B. All patients were followed up for 6 months. No recurrence was seen in either group. Conclusion: Conjunctival autograft with autologous serum is a safe and fast method. It is equally effective as conventional sutured autograft technique. Post operative discomfort is significantly less in this method. It also prevents suture related complications.
Authors and Affiliations
Anita Minj
Keywords
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