Continuous Production of Fenofibrate Solid Lipid Nanoparticles by Hot-Melt Extrusion Technology: a Systematic Study Based on a Quality by Design Approach
Journal Title: The AAPS Journal - Year 2015, Vol 17, Issue 1
Abstract
The online version of this article (doi:10.1208/s12248-014-9674-8) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Hemlata Patil, Xin Feng, Xingyou Ye, Soumyajit Majumdar, Michael A. Repka
Keywords
Related Articles
- EP ID EP680905
- DOI 10.1208/s12248-014-9674-8
- Views 37
- Downloads 0
Determination of the Most Influential Sources of Variability in Tacrolimus Trough Blood Concentrations in Adult Liver Transplant Recipients: A Bottom-Up Approach
The online version of this article (doi:10.1208/s12248-014-9577-8) contains supplementary material, which is available to authorized users.
Evaluation of Nanosuspensions for Absorption Enhancement of Poorly Soluble Drugs: In Vitro Transport Studies Across Intestinal Epithelial Monolayers
Budesonide and spironolactone nanosuspensions type DissoCubes® were manufactured by high-pressure piston gap homogenization (Emulsiflex®-C50, Avestin Inc, Ottawa, Canada). Budesonide nanosuspension consis...
Cannabinoid receptors and endocannabinoids: Evidence for new players
It is now well established that the psychoactive effects ofCannabis sativa are primarily mediated through neuronal CB1 receptors, while its therapeutic immune properties are primarily mediated through CB2 receptors. Two...
Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats
Inclusion of stochastic differential equations in mixed effects models provides means to quantify and distinguish three sources of variability in data. In addition to the two commonly encountered sources, measurement err...
Investigation of the Ovarian and Prostate Cancer Peptidome for Candidate Early Detection Markers Using a Novel Nanoparticle Biomarker Capture Technology
Current efforts to identify protein biomarkers of disease use mainly mass spectrometry (MS) to analyze tissue and blood specimens. The low-molecular-weight “peptidome” is an attractive information archive...