Contrast induced nephropathy - cardiologist perspective
Journal Title: Nepalese Heart Journal - Year 2013, Vol 10, Issue 1
Abstract
Use of contrast media for cardiovascular intervention is associated with risk of contrast induced nephropathy. Contrast induced nephropathy is associated with increased morbidity, prolonged hospitalization, potential need for dialysis and increased mortality rate. Although the consequences of contrast induced nephropathy are well known, the prospective identifcation of patient at risk for nephropathy has been inconsistent. The mechanism of contrast induced nephropathy is complex and not fully understood. Direct tubular toxicity and disturbances of renal hemodynamic with altered glomerular fltration and renal medullary ischemia are the most important path-physiological mechanism. Prevention of contrast induced nephropathy is address in numerous studies. The most attractive agents include hydration, N-acetylcysteine, and infusion of sodium bicarbonate. This review focuses on the defnition, pathophysiology and prevention of contrast induced nephropathy.
Authors and Affiliations
Sanjib Kumar Sharma| Department of Cardiology, College of Medical Sciences, Bharatpur, Nepal, Laxman Dubey| Department of Cardiology, College of Medical Sciences, Bharatpur, Nepal, Sogunuru Guruprasad| Department of Cardiology, College of Medical Sciences, Bharatpur, Nepal, Gangapatnam Subramanyam| Department of Cardiology, College of Medical Sciences, Bharatpur, Nepal
Keywords
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- EP ID EP15728
- DOI http://dx.doi.org/10.3126/njh.v10i1.9745
- Views 394
- Downloads 19
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