Cooperation between heat shock proteins in organizing of proteins spatial structure
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2014, Vol 68, Issue
Abstract
Heat shock proteins (Hsps) are a class of proteins with highly conserved amino acid sequences. They are widespread in nature; they are found in archeons, true bacteria and eukaryotic organisms. Hsps from various families, commonly interact to execute essential cellular tasks, such as molecular regulation of newly synthesized protein-folding or restoration of the appropriate conformation of denatured and aggregated proteins. In this review we discuss mechanisms of spatial organization of protein structure mediated by Hsp10, Hsp40, Hsp60, Hsp70, Hsp104 (Hsp100) and Hsp110. Interactions between Hsps of different molecular weights are described.
Authors and Affiliations
Zbigniew Wyżewski, Karolina P. Gregorczyk, Lidia Szulc-Dąbrowska, Justyna Struzik, Joanna Szczepanowska, Marek Niemiałtowski
Keywords
Related Articles
- EP ID EP67413
- DOI -
- Views 138
- Downloads 0
Potential protective effect of ovocystatin on aging-related cognitive impairment in rats
Introduction: Increased occurrence of cognitive deficits in mild cognitive impairment is related with the phenomenon of aging within the population. Cystatin C has been associated with cysteine protease inhibiting proper...
Interferons: between structure and function
Interferons are a family of proteins that are released by a variety of cells in response to infections caused by viruses. Currently, we distinguish three types of interferons. They are classified based on the nucleotide...
Nontuberculous mycobacteria: M. marinum, M. ulcerans, M. xenopi – brief characteristics of the bacteria and diseases caused by them
Mycobacterium is a variable group of acid-fast bacillus which contains pathogenic bacteria causing tuberculosis (MTC – Mycobacterium tuberculosis complex) and leprosy (M. leprae) as well as numerous nontuberculous mycoba...
Naturalne związki zaangażowane w kontrolę masy tkanki tłuszczowej w badaniach in vitro
Światowa Organizacja Zdrowia (WHO) uznała otyłość za epidemię XXI wieku. Otyłość to patologiczne nagromadzenie tkanki tłuszczowej w ustroju uwarunkowane wieloma czynnikami: metabolicznymi, endokrynologicznymi, genetyczny...
Vegetables and fruit, as a source of bioactive substances, and impact on memory and cognitive function of elderly
The phenomenon of population aging is not only associated with an increase in the number and proportion of older people in society, but also with an increase in the incidence of cognitive impairment. This can impair the...